![[5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone structure](/static/products/6777/677758-66-6.webp)
[5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone
TL;DR: [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone (CAS 677758-66-6) is a chemical compound with molecular formula C21H20F2N4O and molecular weight 382.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone
Also Known As: [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone|[5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl](6-methyl-3,4-dihydroquinolin-1(2H)-yl)methanone|[5-CYCLOPROPYL-7-(DIFLUOROMETHYL)PYRAZOLO[1,5-A]PYRIMIDIN-3-YL][6-METHYL-3,4-DIHYDRO-1(2H)-QUINOLINYL]METHANONE
| Molecular Formula | C21H20F2N4O |
|---|---|
| Molecular Weight | 382.16 g/mol |
| LogP | 4.44572 |
| Topological Polar Surface Area | 50.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 382.16052 |
| Heavy Atoms | 28 |
| Complexity | 1087.4442 |
Chemical Identifiers
| CAS Number | 677758-66-6 |
|---|---|
| SMILES | CC1=CC2=C(C=C1)N(CCC2)C(=O)C3=C4N=C(C=C(N4N=C3)C(F)F)C5CC5 |
Product Overview
[5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone (CAS 677758-66-6), with molecular formula C21H20F2N4O and molecular weight 382.16 g/mol. IUPAC: [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone.
Chemical Property Profile of [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone
Property Insights of [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone
The XLogP value of 4.44572 indicates that [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 50.5 Ų, [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone?
The CAS number of [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone is 677758-66-6.
What is the molecular formula of [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone?
The molecular formula of [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone is C21H20F2N4O.
What is the molecular weight of [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone?
The molecular weight of [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone is 382.16 g/mol.
Where can I buy [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone?
You can request a quote for [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone?
Yes, KEHONG BIO provides custom synthesis services for [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.