5-iodo-2,6-dimethyl-N-(2-thienylmethyl)-4-pyrimidinamine
TL;DR: 5-iodo-2,6-dimethyl-N-(2-thienylmethyl)-4-pyrimidinamine (CAS 677749-62-1) is a chemical compound with molecular formula C11H12IN3S and molecular weight 344.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-iodo-2,6-dimethyl-N-(thiophen-2-ylmethyl)pyrimidin-4-amine
Also Known As: 5-iodo-2,6-dimethyl-N-(2-thienylmethyl)-4-pyrimidinamine, 9P-754, 5-iodo-2,6-dimethyl-N-(thiophen-2-ylmethyl)pyrimidin-4-amine, 5-iodo-2,6-dimethyl-N-[(thiophen-2-yl)methyl]pyrimidin-4-amine
| Molecular Formula | C11H12IN3S |
|---|---|
| Molecular Weight | 344.98 g/mol |
| LogP | 3.37164 |
| Topological Polar Surface Area | 37.81 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 344.97968 |
| Heavy Atoms | 16 |
| Complexity | 482.22495 |
Chemical Identifiers
| CAS Number | 677749-62-1 |
|---|---|
| SMILES | CC1=C(C(=NC(=N1)C)NCC2=CC=CS2)I |
Product Overview
5-iodo-2,6-dimethyl-N-(2-thienylmethyl)-4-pyrimidinamine (CAS 677749-62-1), with molecular formula C11H12IN3S and molecular weight 344.98 g/mol. IUPAC: 5-iodo-2,6-dimethyl-N-(thiophen-2-ylmethyl)pyrimidin-4-amine.
Chemical Property Profile of 5-iodo-2,6-dimethyl-N-(2-thienylmethyl)-4-pyrimidinamine
Property Insights of 5-iodo-2,6-dimethyl-N-(2-thienylmethyl)-4-pyrimidinamine
The XLogP value of 3.37164 indicates that 5-iodo-2,6-dimethyl-N-(2-thienylmethyl)-4-pyrimidinamine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.81 Ų, 5-iodo-2,6-dimethyl-N-(2-thienylmethyl)-4-pyrimidinamine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-iodo-2,6-dimethyl-N-(2-thienylmethyl)-4-pyrimidinamine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-iodo-2,6-dimethyl-N-(2-thienylmethyl)-4-pyrimidinamine?
The CAS number of 5-iodo-2,6-dimethyl-N-(2-thienylmethyl)-4-pyrimidinamine is 677749-62-1.
What is the molecular formula of 5-iodo-2,6-dimethyl-N-(2-thienylmethyl)-4-pyrimidinamine?
The molecular formula of 5-iodo-2,6-dimethyl-N-(2-thienylmethyl)-4-pyrimidinamine is C11H12IN3S.
What is the molecular weight of 5-iodo-2,6-dimethyl-N-(2-thienylmethyl)-4-pyrimidinamine?
The molecular weight of 5-iodo-2,6-dimethyl-N-(2-thienylmethyl)-4-pyrimidinamine is 344.98 g/mol.
Where can I buy 5-iodo-2,6-dimethyl-N-(2-thienylmethyl)-4-pyrimidinamine?
You can request a quote for 5-iodo-2,6-dimethyl-N-(2-thienylmethyl)-4-pyrimidinamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-iodo-2,6-dimethyl-N-(2-thienylmethyl)-4-pyrimidinamine?
Yes, KEHONG BIO provides custom synthesis services for 5-iodo-2,6-dimethyl-N-(2-thienylmethyl)-4-pyrimidinamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.