AH-487/42273574
TL;DR: AH-487/42273574 (CAS 677735-16-9) is a chemical compound with molecular formula C18H21N3O5S2 and molecular weight 423.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
diethyl 3-methyl-5-[[2-(4-methylpyrimidin-2-yl)sulfanylacetyl]amino]thiophene-2,4-dicarboxylate
Also Known As: AH-487/42273574, diethyl3-methyl-5-({[(4-methyl-2-pyrimidinyl)thio]acetyl}amino)-2,4-thiophenedicarboxylate, diethyl 3-methyl-5-[[2-(4-methylpyrimidin-2-yl)sulfanylacetyl]amino]thiophene-2,4-dicarboxylate, diethyl 3-methyl-5-(2-((4-methylpyrimidin-2-yl)thio)acetamido)thiophene-2,4-dicarboxylate, diethyl 3-methyl-5-({[(4-methylpyrimidin-2-yl)sulfanyl]acetyl}amino)thiophene-2,4-dicarboxylate
| Molecular Formula | C18H21N3O5S2 |
|---|---|
| Molecular Weight | 423.09 g/mol |
| LogP | 3.23914 |
| Topological Polar Surface Area | 107.48 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 8 |
| Exact Mass | 423.09225 |
| Heavy Atoms | 28 |
| Complexity | 882.1012 |
Chemical Identifiers
| CAS Number | 677735-16-9 |
|---|---|
| SMILES | CCOC(=O)C1=C(SC(=C1C)C(=O)OCC)NC(=O)CSC2=NC=CC(=N2)C |
Product Overview
AH-487/42273574 (CAS 677735-16-9), with molecular formula C18H21N3O5S2 and molecular weight 423.09 g/mol. IUPAC: diethyl 3-methyl-5-[[2-(4-methylpyrimidin-2-yl)sulfanylacetyl]amino]thiophene-2,4-dicarboxylate.
Chemical Property Profile of AH-487/42273574
Property Insights of AH-487/42273574
The XLogP value of 3.23914 indicates that AH-487/42273574 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 107.48 Ų falls within the moderate polarity range, balancing permeability and solubility for AH-487/42273574. Following Lipinski's Rule of Five, AH-487/42273574 has 1 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AH-487/42273574?
The CAS number of AH-487/42273574 is 677735-16-9.
What is the molecular formula of AH-487/42273574?
The molecular formula of AH-487/42273574 is C18H21N3O5S2.
What is the molecular weight of AH-487/42273574?
The molecular weight of AH-487/42273574 is 423.09 g/mol.
Where can I buy AH-487/42273574?
You can request a quote for AH-487/42273574 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AH-487/42273574?
Yes, KEHONG BIO provides custom synthesis services for AH-487/42273574 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.