iCRT 14
TL;DR: iCRT 14 (CAS 677331-12-3) is a chemical compound with molecular formula C21H17N3O2S and molecular weight 375.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-[(2,5-dimethyl-1-pyridin-3-ylpyrrol-3-yl)methylidene]-3-phenyl-1,3-thiazolidine-2,4-dione
Also Known As: iCRT 14, ChemDiv3_003727, 5-[(2,5-dimethyl-1-pyridin-3-ylpyrrol-3-yl)methylidene]-3-phenyl-1,3-thiazolidine-2,4-dione, 5-[[2,5-dimethyl-1-(3-pyridyl)pyrrol-3-yl]methylene]-3-phenyl-thiazolidine-2,4-dione, (5Z)-5-{[2,5-DIMETHYL-1-(PYRIDIN-3-YL)PYRROL-3-YL]METHYLIDENE}-3-PHENYL-1,3-THIAZOLIDINE-2,4-DIONE
| Molecular Formula | C21H17N3O2S |
|---|---|
| Molecular Weight | 375.10 g/mol |
| LogP | 4.73004 |
| Topological Polar Surface Area | 55.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 375.10416 |
| Heavy Atoms | 27 |
| Complexity | 1055.7906 |
Chemical Identifiers
| CAS Number | 677331-12-3 |
|---|---|
| SMILES | CC1=CC(=C(N1C2=CN=CC=C2)C)C=C3C(=O)N(C(=O)S3)C4=CC=CC=C4 |
Product Overview
iCRT 14 (CAS 677331-12-3), with molecular formula C21H17N3O2S and molecular weight 375.10 g/mol. IUPAC: 5-[(2,5-dimethyl-1-pyridin-3-ylpyrrol-3-yl)methylidene]-3-phenyl-1,3-thiazolidine-2,4-dione.
Chemical Property Profile of iCRT 14
Property Insights of iCRT 14
The XLogP value of 4.73004 indicates that iCRT 14 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.2 Ų, iCRT 14 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, iCRT 14 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of iCRT 14?
The CAS number of iCRT 14 is 677331-12-3.
What is the molecular formula of iCRT 14?
The molecular formula of iCRT 14 is C21H17N3O2S.
What is the molecular weight of iCRT 14?
The molecular weight of iCRT 14 is 375.10 g/mol.
Where can I buy iCRT 14?
You can request a quote for iCRT 14 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for iCRT 14?
Yes, KEHONG BIO provides custom synthesis services for iCRT 14 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.