![4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(3-fluorophenyl)sulfonyl]-1-piperazinecarboxamide structure](/static/products/6773/677302-45-3.webp)
4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(3-fluorophenyl)sulfonyl]-1-piperazinecarboxamide
TL;DR: 4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(3-fluorophenyl)sulfonyl]-1-piperazinecarboxamide (CAS 677302-45-3) is a chemical compound with molecular formula C17H15ClF4N4O3S and molecular weight 466.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(3-fluorophenyl)sulfonylpiperazine-1-carboxamide
Also Known As: 4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(3-fluorophenyl)sulfonyl]-1-piperazinecarboxamide, 4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(3-fluorobenzene-1-sulfonyl)piperazine-1-carboxamide, 4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(3-fluorophenyl)sulfonyl-piperazine-1-carboxamide, 4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(3-fluorophenyl)sulfonylpiperazine-1-carboxamide
| Molecular Formula | C17H15ClF4N4O3S |
|---|---|
| Molecular Weight | 466.05 g/mol |
| LogP | 3.1134 |
| Topological Polar Surface Area | 82.61 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 466.04895 |
| Heavy Atoms | 30 |
| Complexity | 1057.2091 |
Chemical Identifiers
| CAS Number | 677302-45-3 |
|---|---|
| SMILES | C1CN(CCN1C2=C(C=C(C=N2)C(F)(F)F)Cl)C(=O)NS(=O)(=O)C3=CC=CC(=C3)F |
Product Overview
4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(3-fluorophenyl)sulfonyl]-1-piperazinecarboxamide (CAS 677302-45-3), with molecular formula C17H15ClF4N4O3S and molecular weight 466.05 g/mol. IUPAC: 4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(3-fluorophenyl)sulfonylpiperazine-1-carboxamide.
Chemical Property Profile of 4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(3-fluorophenyl)sulfonyl]-1-piperazinecarboxamide
Property Insights of 4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(3-fluorophenyl)sulfonyl]-1-piperazinecarboxamide
The XLogP value of 3.1134 indicates that 4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(3-fluorophenyl)sulfonyl]-1-piperazinecarboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 82.61 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(3-fluorophenyl)sulfonyl]-1-piperazinecarboxamide. Following Lipinski's Rule of Five, 4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(3-fluorophenyl)sulfonyl]-1-piperazinecarboxamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(3-fluorophenyl)sulfonyl]-1-piperazinecarboxamide?
The CAS number of 4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(3-fluorophenyl)sulfonyl]-1-piperazinecarboxamide is 677302-45-3.
What is the molecular formula of 4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(3-fluorophenyl)sulfonyl]-1-piperazinecarboxamide?
The molecular formula of 4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(3-fluorophenyl)sulfonyl]-1-piperazinecarboxamide is C17H15ClF4N4O3S.
What is the molecular weight of 4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(3-fluorophenyl)sulfonyl]-1-piperazinecarboxamide?
The molecular weight of 4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(3-fluorophenyl)sulfonyl]-1-piperazinecarboxamide is 466.05 g/mol.
Where can I buy 4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(3-fluorophenyl)sulfonyl]-1-piperazinecarboxamide?
You can request a quote for 4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(3-fluorophenyl)sulfonyl]-1-piperazinecarboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(3-fluorophenyl)sulfonyl]-1-piperazinecarboxamide?
Yes, KEHONG BIO provides custom synthesis services for 4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(3-fluorophenyl)sulfonyl]-1-piperazinecarboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.