![5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide structure](/static/products/6770/677025-06-8.webp)
5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
TL;DR: 5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide (CAS 677025-06-8) is a chemical compound with molecular formula C17H15F2N5O and molecular weight 343.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-cyclopropyl-7-(difluoromethyl)-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
Also Known As: 5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide, 5-cyclopropyl-7-(difluoromethyl)-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide, [7-(difluoromethyl)-5-cyclopropyl(8-hydropyrazolo[1,5-a]pyrimidin-2-yl)]-N-(3- pyridylmethyl)carboxamide, 5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo(1,5-a)pyrimidine-2-carboxamide, 5-Cyclopropyl-7-(difluoromethyl)-N-[(pyridin-3-yl)methyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide
| Molecular Formula | C17H15F2N5O |
|---|---|
| Molecular Weight | 343.12 g/mol |
| LogP | 2.8693 |
| Topological Polar Surface Area | 72.18 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 343.12448 |
| Heavy Atoms | 25 |
| Complexity | 921.43787 |
Chemical Identifiers
| CAS Number | 677025-06-8 |
|---|---|
| SMILES | C1CC1C2=NC3=CC(=NN3C(=C2)C(F)F)C(=O)NCC4=CN=CC=C4 |
Product Overview
5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide (CAS 677025-06-8), with molecular formula C17H15F2N5O and molecular weight 343.12 g/mol. IUPAC: 5-cyclopropyl-7-(difluoromethyl)-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide.
Chemical Property Profile of 5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
Property Insights of 5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
The XLogP value of 2.8693 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide. The TPSA of 72.18 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide. Following Lipinski's Rule of Five, 5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
The CAS number of 5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide is 677025-06-8.
What is the molecular formula of 5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
The molecular formula of 5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide is C17H15F2N5O.
What is the molecular weight of 5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
The molecular weight of 5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide is 343.12 g/mol.
Where can I buy 5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
You can request a quote for 5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for 5-Cyclopropyl-7-(difluoromethyl)-N-(3-pyridinylmethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.