1-isopropyl-6-methyl-1H-indole-3-carboxylic acid thiazol-2-ylamide
TL;DR: 1-isopropyl-6-methyl-1H-indole-3-carboxylic acid thiazol-2-ylamide (CAS 676476-81-6) is a chemical compound with molecular formula C16H17N3OS and molecular weight 299.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-methyl-1-propan-2-yl-N-(1,3-thiazol-2-yl)indole-3-carboxamide
Also Known As: 1-isopropyl-6-methyl-1H-indole-3-carboxylic acid thiazol-2-ylamide, 6-methyl-1-propan-2-yl-N-(1,3-thiazol-2-yl)indole-3-carboxamide, 1H-Indole-3-carboxamide, 6-methyl-1-(1-methylethyl)-N-2-thiazolyl-, 6-Methyl-1-(propan-2-yl)-N-(1,3-thiazol-2-yl)-1H-indole-3-carboxamide
| Molecular Formula | C16H17N3OS |
|---|---|
| Molecular Weight | 299.11 g/mol |
| LogP | 4.23942 |
| Topological Polar Surface Area | 46.92 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 299.10922 |
| Heavy Atoms | 21 |
| Complexity | 787.31964 |
Chemical Identifiers
| CAS Number | 676476-81-6 |
|---|---|
| SMILES | CC1=CC2=C(C=C1)C(=CN2C(C)C)C(=O)NC3=NC=CS3 |
Product Overview
1-isopropyl-6-methyl-1H-indole-3-carboxylic acid thiazol-2-ylamide (CAS 676476-81-6), with molecular formula C16H17N3OS and molecular weight 299.11 g/mol. IUPAC: 6-methyl-1-propan-2-yl-N-(1,3-thiazol-2-yl)indole-3-carboxamide.
Chemical Property Profile of 1-isopropyl-6-methyl-1H-indole-3-carboxylic acid thiazol-2-ylamide
Property Insights of 1-isopropyl-6-methyl-1H-indole-3-carboxylic acid thiazol-2-ylamide
The XLogP value of 4.23942 indicates that 1-isopropyl-6-methyl-1H-indole-3-carboxylic acid thiazol-2-ylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 46.92 Ų, 1-isopropyl-6-methyl-1H-indole-3-carboxylic acid thiazol-2-ylamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-isopropyl-6-methyl-1H-indole-3-carboxylic acid thiazol-2-ylamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-isopropyl-6-methyl-1H-indole-3-carboxylic acid thiazol-2-ylamide?
The CAS number of 1-isopropyl-6-methyl-1H-indole-3-carboxylic acid thiazol-2-ylamide is 676476-81-6.
What is the molecular formula of 1-isopropyl-6-methyl-1H-indole-3-carboxylic acid thiazol-2-ylamide?
The molecular formula of 1-isopropyl-6-methyl-1H-indole-3-carboxylic acid thiazol-2-ylamide is C16H17N3OS.
What is the molecular weight of 1-isopropyl-6-methyl-1H-indole-3-carboxylic acid thiazol-2-ylamide?
The molecular weight of 1-isopropyl-6-methyl-1H-indole-3-carboxylic acid thiazol-2-ylamide is 299.11 g/mol.
Where can I buy 1-isopropyl-6-methyl-1H-indole-3-carboxylic acid thiazol-2-ylamide?
You can request a quote for 1-isopropyl-6-methyl-1H-indole-3-carboxylic acid thiazol-2-ylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-isopropyl-6-methyl-1H-indole-3-carboxylic acid thiazol-2-ylamide?
Yes, KEHONG BIO provides custom synthesis services for 1-isopropyl-6-methyl-1H-indole-3-carboxylic acid thiazol-2-ylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.