(2-Chloro-4-fluorophenyl)acetyl chloride
TL;DR: (2-Chloro-4-fluorophenyl)acetyl chloride (CAS 676348-45-1) is a chemical compound with molecular formula C8H5Cl2FO and molecular weight 205.97 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(2-chloro-4-fluorophenyl)acetyl chloride
Also Known As: (2-Chloro-4-fluorophenyl)acetyl chloride, -ACETYLCHLORIDE, 2-(2-chloro-4-fluorophenyl)acetyl chloride, (2-chloro-4-fluoro-phenyl)-acetyl chloride, 2-chloro-4-fluorophenylacetyl chloride
| Molecular Formula | C8H5Cl2FO |
|---|---|
| Molecular Weight | 205.97 g/mol |
| LogP | 2.787 |
| Topological Polar Surface Area | 17.07 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 205.97015 |
| Heavy Atoms | 12 |
| Complexity | 311.9262 |
Chemical Identifiers
| CAS Number | 676348-45-1 |
|---|---|
| SMILES | C1=CC(=C(C=C1F)Cl)CC(=O)Cl |
Product Overview
(2-Chloro-4-fluorophenyl)acetyl chloride (CAS 676348-45-1), with molecular formula C8H5Cl2FO and molecular weight 205.97 g/mol. IUPAC: 2-(2-chloro-4-fluorophenyl)acetyl chloride.
Chemical Property Profile of (2-Chloro-4-fluorophenyl)acetyl chloride
Property Insights of (2-Chloro-4-fluorophenyl)acetyl chloride
The XLogP value of 2.787 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (2-Chloro-4-fluorophenyl)acetyl chloride. With a topological polar surface area (TPSA) of 17.07 Ų, (2-Chloro-4-fluorophenyl)acetyl chloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (2-Chloro-4-fluorophenyl)acetyl chloride has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2-Chloro-4-fluorophenyl)acetyl chloride?
The CAS number of (2-Chloro-4-fluorophenyl)acetyl chloride is 676348-45-1.
What is the molecular formula of (2-Chloro-4-fluorophenyl)acetyl chloride?
The molecular formula of (2-Chloro-4-fluorophenyl)acetyl chloride is C8H5Cl2FO.
What is the molecular weight of (2-Chloro-4-fluorophenyl)acetyl chloride?
The molecular weight of (2-Chloro-4-fluorophenyl)acetyl chloride is 205.97 g/mol.
Where can I buy (2-Chloro-4-fluorophenyl)acetyl chloride?
You can request a quote for (2-Chloro-4-fluorophenyl)acetyl chloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2-Chloro-4-fluorophenyl)acetyl chloride?
Yes, KEHONG BIO provides custom synthesis services for (2-Chloro-4-fluorophenyl)acetyl chloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.