1-(2-Pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine dihydrochloride structure

1-(2-Pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine dihydrochloride

TL;DR: 1-(2-Pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine dihydrochloride (CAS 67464-99-7) is a chemical compound with molecular formula C20H28Cl2N4O4 and molecular weight 458.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-(4-pyrimidin-2-ylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)propan-1-one;dihydrochloride

Also Known As: 1-(2-Pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine dihydrochloride, Propiophenone, 3-(4-(2-pyrimidyl)piperazinyl)-3',4',5'-trimethoxy-, dihydrochloride, 3-(4-(2-Pyrimidyl)piperazinyl)-3',4',5'-trimethoxypropiophenone dihydrochloride, Piperazine, 1-(2-pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)-, dihydrochloride, 3-(4-pyrimidin-2-ylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)propan-1-one dihydrochloride

CAS: 67464-99-7
Molecular Formula C20H28Cl2N4O4
Molecular Weight 458.15 g/mol
LogP 2.741
Topological Polar Surface Area 77.02 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 8
Rotatable Bonds 8
Exact Mass 458.14877
Heavy Atoms 30
Complexity 777.6435

Chemical Identifiers

CAS Number 67464-99-7
SMILES COC1=CC(=CC(=C1OC)OC)C(=O)CCN2CCN(CC2)C3=NC=CC=N3.Cl.Cl

Product Overview

1-(2-Pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine dihydrochloride (CAS 67464-99-7), with molecular formula C20H28Cl2N4O4 and molecular weight 458.15 g/mol. IUPAC: 3-(4-pyrimidin-2-ylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)propan-1-one;dihydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 1-(2-Pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine dihydrochloride

XLogP
2.741
TPSA (Topological Polar Surface Area)
77.02
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
8
Rotatable Bonds
8
Heavy Atoms
30
Complexity
777.6435
Exact Mass
458.14877
Monoisotopic Mass
458.14877
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 1-(2-Pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine dihydrochloride

The XLogP value of 2.741 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(2-Pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine dihydrochloride. The TPSA of 77.02 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(2-Pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine dihydrochloride. Following Lipinski's Rule of Five, 1-(2-Pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine dihydrochloride has 0 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 1-(2-Pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine dihydrochloride?

The CAS number of 1-(2-Pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine dihydrochloride is 67464-99-7.

What is the molecular formula of 1-(2-Pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine dihydrochloride?

The molecular formula of 1-(2-Pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine dihydrochloride is C20H28Cl2N4O4.

What is the molecular weight of 1-(2-Pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine dihydrochloride?

The molecular weight of 1-(2-Pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine dihydrochloride is 458.15 g/mol.

Where can I buy 1-(2-Pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine dihydrochloride?

You can request a quote for 1-(2-Pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine dihydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 1-(2-Pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine dihydrochloride?

Yes, KEHONG BIO provides custom synthesis services for 1-(2-Pyrimidyl)-4-(3,4,5-trimethoxybenzoylethyl)piperazine dihydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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