![(5E)-2-(4-methylpiperazin-1-yl)-5-({4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,5-dihydro-1,3-thiazol-4-one structure](/static/products/6743/674350-14-2.webp)
(5E)-2-(4-methylpiperazin-1-yl)-5-({4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,5-dihydro-1,3-thiazol-4-one
TL;DR: (5E)-2-(4-methylpiperazin-1-yl)-5-({4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,5-dihydro-1,3-thiazol-4-one (CAS 674350-14-2) is a chemical compound with molecular formula C22H22N4O4S and molecular weight 438.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-2-(4-methylpiperazin-1-yl)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-1,3-thiazol-4-one
Also Known As: (5E)-2-(4-methylpiperazin-1-yl)-5-({4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,5-dihydro-1,3-thiazol-4-one, (Z)-2-(4-methylpiperazin-1-yl)-5-(4-((4-nitrobenzyl)oxy)benzylidene)thiazol-4(5H)-one, (5Z)-2-(4-methylpiperazin-1-yl)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-1,3-thiazol-4-one, (5Z)-2-(4-methylpiperazin-1-yl)-5-{4-[(4-nitrobenzyl)oxy]benzylidene}-1,3-thiazol-4(5H)-one
| Molecular Formula | C22H22N4O4S |
|---|---|
| Molecular Weight | 438.14 g/mol |
| LogP | 3.3915 |
| Topological Polar Surface Area | 88.28 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Exact Mass | 438.13617 |
| Heavy Atoms | 31 |
| Complexity | 1026.4813 |
Chemical Identifiers
| CAS Number | 674350-14-2 |
|---|---|
| SMILES | CN1CCN(CC1)C2=NC(=O)/C(=C/C3=CC=C(C=C3)OCC4=CC=C(C=C4)[N+](=O)[O-])/S2 |
Product Overview
(5E)-2-(4-methylpiperazin-1-yl)-5-({4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,5-dihydro-1,3-thiazol-4-one (CAS 674350-14-2), with molecular formula C22H22N4O4S and molecular weight 438.14 g/mol. IUPAC: (5Z)-2-(4-methylpiperazin-1-yl)-5-[[4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-1,3-thiazol-4-one.
Chemical Property Profile of (5E)-2-(4-methylpiperazin-1-yl)-5-({4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,5-dihydro-1,3-thiazol-4-one
Property Insights of (5E)-2-(4-methylpiperazin-1-yl)-5-({4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,5-dihydro-1,3-thiazol-4-one
The XLogP value of 3.3915 indicates that (5E)-2-(4-methylpiperazin-1-yl)-5-({4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,5-dihydro-1,3-thiazol-4-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 88.28 Ų falls within the moderate polarity range, balancing permeability and solubility for (5E)-2-(4-methylpiperazin-1-yl)-5-({4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,5-dihydro-1,3-thiazol-4-one. Following Lipinski's Rule of Five, (5E)-2-(4-methylpiperazin-1-yl)-5-({4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,5-dihydro-1,3-thiazol-4-one has 0 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (5E)-2-(4-methylpiperazin-1-yl)-5-({4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,5-dihydro-1,3-thiazol-4-one?
The CAS number of (5E)-2-(4-methylpiperazin-1-yl)-5-({4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,5-dihydro-1,3-thiazol-4-one is 674350-14-2.
What is the molecular formula of (5E)-2-(4-methylpiperazin-1-yl)-5-({4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,5-dihydro-1,3-thiazol-4-one?
The molecular formula of (5E)-2-(4-methylpiperazin-1-yl)-5-({4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,5-dihydro-1,3-thiazol-4-one is C22H22N4O4S.
What is the molecular weight of (5E)-2-(4-methylpiperazin-1-yl)-5-({4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,5-dihydro-1,3-thiazol-4-one?
The molecular weight of (5E)-2-(4-methylpiperazin-1-yl)-5-({4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,5-dihydro-1,3-thiazol-4-one is 438.14 g/mol.
Where can I buy (5E)-2-(4-methylpiperazin-1-yl)-5-({4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,5-dihydro-1,3-thiazol-4-one?
You can request a quote for (5E)-2-(4-methylpiperazin-1-yl)-5-({4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,5-dihydro-1,3-thiazol-4-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (5E)-2-(4-methylpiperazin-1-yl)-5-({4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,5-dihydro-1,3-thiazol-4-one?
Yes, KEHONG BIO provides custom synthesis services for (5E)-2-(4-methylpiperazin-1-yl)-5-({4-[(4-nitrophenyl)methoxy]phenyl}methylidene)-4,5-dihydro-1,3-thiazol-4-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.