18-Hydroxyprostaglandin E2
TL;DR: 18-Hydroxyprostaglandin E2 (CAS 67355-95-7) is a chemical compound with molecular formula C20H32O6 and molecular weight 368.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(Z)-7-[(1R,2R,3R)-2-[(E,3S)-3,6-dihydroxyoct-1-enyl]-3-hydroxy-5-oxocyclopentyl]hept-5-enoic acid
Also Known As: 18-Hydroxyprostaglandin E2, 18-Hydroxy-PGE2, Benzene, 1,2-difluoro-4-isocyano- (9CI), (Z)-7-[(1R,2R,3R)-2-[(E,3S)-3,6-dihydroxyoct-1-enyl]-3-hydroxy-5-oxocyclopentyl]hept-5-enoic acid, Prosta-5,13-dien-1-oic acid, 11,15,18-trihydroxy-9-oxo-, (5Z,11alpha,13E,15S)-
| Molecular Formula | C20H32O6 |
|---|---|
| Molecular Weight | 368.22 g/mol |
| LogP | 2.2219 |
| Topological Polar Surface Area | 115.06 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 12 |
| Exact Mass | 368.21988 |
| Heavy Atoms | 26 |
| Complexity | 498.52988 |
Chemical Identifiers
| CAS Number | 67355-95-7 |
|---|---|
| SMILES | CCC(CC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1C/C=C\CCCC(=O)O)O)O)O |
Product Overview
18-Hydroxyprostaglandin E2 (CAS 67355-95-7), with molecular formula C20H32O6 and molecular weight 368.22 g/mol. IUPAC: (Z)-7-[(1R,2R,3R)-2-[(E,3S)-3,6-dihydroxyoct-1-enyl]-3-hydroxy-5-oxocyclopentyl]hept-5-enoic acid.
Chemical Property Profile of 18-Hydroxyprostaglandin E2
Property Insights of 18-Hydroxyprostaglandin E2
The XLogP value of 2.2219 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 18-Hydroxyprostaglandin E2. The TPSA of 115.06 Ų falls within the moderate polarity range, balancing permeability and solubility for 18-Hydroxyprostaglandin E2. Following Lipinski's Rule of Five, 18-Hydroxyprostaglandin E2 has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 18-Hydroxyprostaglandin E2?
The CAS number of 18-Hydroxyprostaglandin E2 is 67355-95-7.
What is the molecular formula of 18-Hydroxyprostaglandin E2?
The molecular formula of 18-Hydroxyprostaglandin E2 is C20H32O6.
What is the molecular weight of 18-Hydroxyprostaglandin E2?
The molecular weight of 18-Hydroxyprostaglandin E2 is 368.22 g/mol.
Where can I buy 18-Hydroxyprostaglandin E2?
You can request a quote for 18-Hydroxyprostaglandin E2 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 18-Hydroxyprostaglandin E2?
Yes, KEHONG BIO provides custom synthesis services for 18-Hydroxyprostaglandin E2 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.