![(2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]prop-2-enamide structure](/static/products/673/673452-73-8.png)
(2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]prop-2-enamide
TL;DR: (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]prop-2-enamide (CAS 673452-73-8) is a chemical compound with molecular formula C21H19Cl2F3N2O2 and molecular weight 458.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-pyrrolidin-1-yl-5-(trifluoromethyl)phenyl]prop-2-enamide
Also Known As: (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]prop-2-enamide, (E)-3-(3,5-dichloro-2-methoxyphenyl)-N-(2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl)acrylamide, (E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-pyrrolidin-1-yl-5-(trifluoromethyl)phenyl]prop-2-enamide, 3-(3,5-dichloro-2-methoxy-phenyl)-N-[2-pyrrolidin-1-yl-5-(trifluoromethyl)phenyl]prop-2-enamide
| Molecular Formula | C21H19Cl2F3N2O2 |
|---|---|
| Molecular Weight | 458.08 g/mol |
| LogP | 6.2729 |
| Topological Polar Surface Area | 41.57 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 458.07758 |
| Heavy Atoms | 30 |
| Complexity | 971.45435 |
Chemical Identifiers
| CAS Number | 673452-73-8 |
|---|---|
| SMILES | COC1=C(C=C(C=C1Cl)Cl)/C=C/C(=O)NC2=C(C=CC(=C2)C(F)(F)F)N3CCCC3 |
Product Overview
(2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]prop-2-enamide (CAS 673452-73-8), with molecular formula C21H19Cl2F3N2O2 and molecular weight 458.08 g/mol. IUPAC: (E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-pyrrolidin-1-yl-5-(trifluoromethyl)phenyl]prop-2-enamide.
Chemical Property Profile of (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]prop-2-enamide
Property Insights of (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]prop-2-enamide
The XLogP value of 6.2729 indicates that (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]prop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.57 Ų, (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]prop-2-enamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]prop-2-enamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]prop-2-enamide?
The CAS number of (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]prop-2-enamide is 673452-73-8.
What is the molecular formula of (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]prop-2-enamide?
The molecular formula of (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]prop-2-enamide is C21H19Cl2F3N2O2.
What is the molecular weight of (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]prop-2-enamide?
The molecular weight of (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]prop-2-enamide is 458.08 g/mol.
Where can I buy (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]prop-2-enamide?
You can request a quote for (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[2-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.