![(2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}prop-2-enamide structure](/static/products/673/673444-74-1.png)
(2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}prop-2-enamide
TL;DR: (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}prop-2-enamide (CAS 673444-74-1) is a chemical compound with molecular formula C21H23Cl2N3O4S and molecular weight 483.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]prop-2-enamide
Also Known As: (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}prop-2-enamide, (E)-3-(3,5-dichloro-2-methoxyphenyl)-N-(4-(4-(methylsulfonyl)piperazin-1-yl)phenyl)acrylamide, (E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]prop-2-enamide, 3-(3,5-dichloro-2-methoxy-phenyl)-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]prop-2-enamide
| Molecular Formula | C21H23Cl2N3O4S |
|---|---|
| Molecular Weight | 483.08 g/mol |
| LogP | 3.7355 |
| Topological Polar Surface Area | 78.95 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 483.07864 |
| Heavy Atoms | 31 |
| Complexity | 1080.5488 |
Chemical Identifiers
| CAS Number | 673444-74-1 |
|---|---|
| SMILES | COC1=C(C=C(C=C1Cl)Cl)/C=C/C(=O)NC2=CC=C(C=C2)N3CCN(CC3)S(=O)(=O)C |
Product Overview
(2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}prop-2-enamide (CAS 673444-74-1), with molecular formula C21H23Cl2N3O4S and molecular weight 483.08 g/mol. IUPAC: (E)-3-(3,5-dichloro-2-methoxyphenyl)-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]prop-2-enamide.
Chemical Property Profile of (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}prop-2-enamide
Property Insights of (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}prop-2-enamide
The XLogP value of 3.7355 indicates that (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}prop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 78.95 Ų falls within the moderate polarity range, balancing permeability and solubility for (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}prop-2-enamide. Following Lipinski's Rule of Five, (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}prop-2-enamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}prop-2-enamide?
The CAS number of (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}prop-2-enamide is 673444-74-1.
What is the molecular formula of (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}prop-2-enamide?
The molecular formula of (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}prop-2-enamide is C21H23Cl2N3O4S.
What is the molecular weight of (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}prop-2-enamide?
The molecular weight of (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}prop-2-enamide is 483.08 g/mol.
Where can I buy (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}prop-2-enamide?
You can request a quote for (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for (2E)-3-(3,5-dichloro-2-methoxyphenyl)-N-{4-[4-(methylsulfonyl)piperazin-1-yl]phenyl}prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.