Diclofensine structure

Diclofensine

TL;DR: Diclofensine (CAS 67165-56-4) is a chemical compound with molecular formula C17H17Cl2NO and molecular weight 321.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-(3,4-dichlorophenyl)-7-methoxy-2-methyl-3,4-dihydro-1H-isoquinoline

Also Known As: Diclofensine, Diclofensina, Diclofensinum, Moxifensin, hydrochloride

CAS: 67165-56-4
Molecular Formula C17H17Cl2NO
Molecular Weight 321.07 g/mol
LogP 4.5
Topological Polar Surface Area 12.5 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 2
Rotatable Bonds 2
Exact Mass 321.06873
Heavy Atoms 21
Complexity 354.0

Chemical Identifiers

CAS Number 67165-56-4
SMILES CN1CC(C2=C(C1)C=C(C=C2)OC)C3=CC(=C(C=C3)Cl)Cl
InChIKey ZJDCGVDEEHWEIG-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (4 patents) Pharmaceutical Intermediates (108 patents)

Product Overview

Diclofensine (CAS 67165-56-4), with molecular formula C17H17Cl2NO and molecular weight 321.07 g/mol. IUPAC: 4-(3,4-dichlorophenyl)-7-methoxy-2-methyl-3,4-dihydro-1H-isoquinoline.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Diclofensine

XLogP
4.5
TPSA (Topological Polar Surface Area)
12.5
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
2
Rotatable Bonds
2
Heavy Atoms
21
Complexity
354.0
Exact Mass
321.06873
Monoisotopic Mass
321.06873
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Diclofensine

The XLogP value of 4.5 indicates that Diclofensine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.5 Ų, Diclofensine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Diclofensine has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Diclofensine?

The CAS number of Diclofensine is 67165-56-4.

What is the molecular formula of Diclofensine?

The molecular formula of Diclofensine is C17H17Cl2NO.

What is the molecular weight of Diclofensine?

The molecular weight of Diclofensine is 321.07 g/mol.

Where can I buy Diclofensine?

You can request a quote for Diclofensine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Diclofensine?

Yes, KEHONG BIO provides custom synthesis services for Diclofensine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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