F1143-1541
TL;DR: F1143-1541 (CAS 670270-99-2) is a chemical compound with molecular formula C24H20ClF3N4S and molecular weight 488.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(4-chlorophenyl)-6-methyl-4-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]thieno[2,3-d]pyrimidine
Also Known As: F1143-1541, 1-[5-(4-CHLOROPHENYL)-6-METHYLTHIENO[2,3-D]PYRIMIDIN-4-YL]-4-[2-(TRIFLUOROMETHYL)PHENYL]PIPERAZINE, 5-(4-chlorophenyl)-6-methyl-4-(4-(2-(trifluoromethyl)phenyl)piperazin-1-yl)thieno[2,3-d]pyrimidine, 5-(4-chlorophenyl)-6-methyl-4-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]thieno[2,3-d]pyrimidine, 3-(p-chlorophenyl)-2-methyl-4-{4-[o-(trifluoromethyl)phenyl]-1-piperazinyl}-1-thia-5,7-diazaindene
| Molecular Formula | C24H20ClF3N4S |
|---|---|
| Molecular Weight | 488.10 g/mol |
| LogP | 6.66552 |
| Topological Polar Surface Area | 32.26 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 488.10492 |
| Heavy Atoms | 33 |
| Complexity | 1295.556 |
Chemical Identifiers
| CAS Number | 670270-99-2 |
|---|---|
| SMILES | CC1=C(C2=C(N=CN=C2S1)N3CCN(CC3)C4=CC=CC=C4C(F)(F)F)C5=CC=C(C=C5)Cl |
Product Overview
F1143-1541 (CAS 670270-99-2), with molecular formula C24H20ClF3N4S and molecular weight 488.10 g/mol. IUPAC: 5-(4-chlorophenyl)-6-methyl-4-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]thieno[2,3-d]pyrimidine.
Chemical Property Profile of F1143-1541
Property Insights of F1143-1541
The XLogP value of 6.66552 indicates that F1143-1541 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.26 Ų, F1143-1541 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F1143-1541 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F1143-1541?
The CAS number of F1143-1541 is 670270-99-2.
What is the molecular formula of F1143-1541?
The molecular formula of F1143-1541 is C24H20ClF3N4S.
What is the molecular weight of F1143-1541?
The molecular weight of F1143-1541 is 488.10 g/mol.
Where can I buy F1143-1541?
You can request a quote for F1143-1541 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F1143-1541?
Yes, KEHONG BIO provides custom synthesis services for F1143-1541 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.