Norverapamil
TL;DR: Norverapamil (CAS 67018-85-3) is a chemical compound with molecular formula C26H36N2O4 and molecular weight 440.27 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethylamino]-2-propan-2-ylpentanenitrile
Also Known As: Norverapamil, N-demethylverapamil, Verapamil-M nor, Nor-R-Verapamil, Verapamil EP Impurity J
| Molecular Formula | C26H36N2O4 |
|---|---|
| Molecular Weight | 440.27 g/mol |
| LogP | 3.3 |
| Topological Polar Surface Area | 72.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 13 |
| Exact Mass | 440.26752 |
| Heavy Atoms | 32 |
| Complexity | 577.0 |
Chemical Identifiers
| CAS Number | 67018-85-3 |
|---|---|
| SMILES | CC(C)C(CCCNCCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC |
| InChIKey | UPKQNCPKPOLASS-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Norverapamil (CAS 67018-85-3), with molecular formula C26H36N2O4 and molecular weight 440.27 g/mol. IUPAC: 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethylamino]-2-propan-2-ylpentanenitrile.
Chemical Property Profile of Norverapamil
Property Insights of Norverapamil
The XLogP value of 3.3 indicates that Norverapamil is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 72.7 Ų falls within the moderate polarity range, balancing permeability and solubility for Norverapamil. Following Lipinski's Rule of Five, Norverapamil has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Norverapamil?
The CAS number of Norverapamil is 67018-85-3.
What is the molecular formula of Norverapamil?
The molecular formula of Norverapamil is C26H36N2O4.
What is the molecular weight of Norverapamil?
The molecular weight of Norverapamil is 440.27 g/mol.
Where can I buy Norverapamil?
You can request a quote for Norverapamil directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Norverapamil?
Yes, KEHONG BIO provides custom synthesis services for Norverapamil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.