O-Desmethylverapamil (D-703)
TL;DR: O-Desmethylverapamil (D-703) (CAS 67018-80-8) is a chemical compound with molecular formula C26H36N2O4 and molecular weight 440.27 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-(4-hydroxy-3-methoxyphenyl)-2-propan-2-ylpentanenitrile
Also Known As: p-Hydroxy-isoptin, O-Desmethylverapamil (D-703), Verapamil Impurity 37, D-703, PR 23
| Molecular Formula | C26H36N2O4 |
|---|---|
| Molecular Weight | 440.27 g/mol |
| LogP | 3.5 |
| Topological Polar Surface Area | 75.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 12 |
| Exact Mass | 440.26752 |
| Heavy Atoms | 32 |
| Complexity | 592.0 |
Chemical Identifiers
| CAS Number | 67018-80-8 |
|---|---|
| SMILES | CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)O)OC |
| InChIKey | WLKVZSXOMGNZLB-UHFFFAOYSA-N |
Product Overview
O-Desmethylverapamil (D-703) (CAS 67018-80-8), with molecular formula C26H36N2O4 and molecular weight 440.27 g/mol. IUPAC: 5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-(4-hydroxy-3-methoxyphenyl)-2-propan-2-ylpentanenitrile.
Chemical Property Profile of O-Desmethylverapamil (D-703)
Property Insights of O-Desmethylverapamil (D-703)
The XLogP value of 3.5 indicates that O-Desmethylverapamil (D-703) is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.0 Ų falls within the moderate polarity range, balancing permeability and solubility for O-Desmethylverapamil (D-703). Following Lipinski's Rule of Five, O-Desmethylverapamil (D-703) has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of O-Desmethylverapamil (D-703)?
The CAS number of O-Desmethylverapamil (D-703) is 67018-80-8.
What is the molecular formula of O-Desmethylverapamil (D-703)?
The molecular formula of O-Desmethylverapamil (D-703) is C26H36N2O4.
What is the molecular weight of O-Desmethylverapamil (D-703)?
The molecular weight of O-Desmethylverapamil (D-703) is 440.27 g/mol.
Where can I buy O-Desmethylverapamil (D-703)?
You can request a quote for O-Desmethylverapamil (D-703) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for O-Desmethylverapamil (D-703)?
Yes, KEHONG BIO provides custom synthesis services for O-Desmethylverapamil (D-703) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.