Tiodazosin
TL;DR: Tiodazosin (CAS 66969-81-1) is a chemical compound with molecular formula C18H21N7O4S and molecular weight 431.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(5-methylsulfanyl-1,3,4-oxadiazol-2-yl)methanone
Also Known As: Tiodazosin, Tiodazosina, Tiodazosine, Tiodazosinum, Tiodazosin [USAN:INN]
| Molecular Formula | C18H21N7O4S |
|---|---|
| Molecular Weight | 431.14 g/mol |
| LogP | 1.6 |
| Topological Polar Surface Area | 158.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 11 |
| Rotatable Bonds | 5 |
| Exact Mass | 431.13757 |
| Heavy Atoms | 30 |
| Complexity | 597.0 |
Chemical Identifiers
| CAS Number | 66969-81-1 |
|---|---|
| SMILES | COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4=NN=C(O4)SC)N)OC |
| InChIKey | MULPYFRDYRZMDS-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Tiodazosin (CAS 66969-81-1), with molecular formula C18H21N7O4S and molecular weight 431.14 g/mol. IUPAC: [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(5-methylsulfanyl-1,3,4-oxadiazol-2-yl)methanone.
Chemical Property Profile of Tiodazosin
Property Insights of Tiodazosin
The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tiodazosin. The TPSA of 158.0 Ų indicates high polarity, suggesting Tiodazosin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Tiodazosin has 1 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tiodazosin?
The CAS number of Tiodazosin is 66969-81-1.
What is the molecular formula of Tiodazosin?
The molecular formula of Tiodazosin is C18H21N7O4S.
What is the molecular weight of Tiodazosin?
The molecular weight of Tiodazosin is 431.14 g/mol.
Where can I buy Tiodazosin?
You can request a quote for Tiodazosin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tiodazosin?
Yes, KEHONG BIO provides custom synthesis services for Tiodazosin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.