Norethindrone 3-(O-dimethylaminopropyl)oxime
TL;DR: Norethindrone 3-(O-dimethylaminopropyl)oxime (CAS 66841-21-2) is a chemical compound with molecular formula C25H38N2O2 and molecular weight 398.29 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8R,9S,10R,13S,14S,17R)-3-[3-(dimethylamino)propoxyimino]-17-ethynyl-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol
Also Known As: Norethindrone 3-(O-dimethylaminopropyl)oxime, 19-Norpregn-4-en-20-yn-3-one, 17-hydroxy-, (3-(dimethylamino)propyl)oxime, (17alpha)-
| Molecular Formula | C25H38N2O2 |
|---|---|
| Molecular Weight | 398.29 g/mol |
| LogP | 3.9 |
| Topological Polar Surface Area | 45.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 398.29333 |
| Heavy Atoms | 29 |
| Complexity | 732.0 |
Chemical Identifiers
| CAS Number | 66841-21-2 |
|---|---|
| SMILES | C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC(=NOCCCN(C)C)CC[C@H]34 |
| InChIKey | SYGKSBXFYOWNQM-AIOSZGMZSA-N |
Product Overview
Norethindrone 3-(O-dimethylaminopropyl)oxime (CAS 66841-21-2), with molecular formula C25H38N2O2 and molecular weight 398.29 g/mol. IUPAC: (8R,9S,10R,13S,14S,17R)-3-[3-(dimethylamino)propoxyimino]-17-ethynyl-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol.
Chemical Property Profile of Norethindrone 3-(O-dimethylaminopropyl)oxime
Property Insights of Norethindrone 3-(O-dimethylaminopropyl)oxime
The XLogP value of 3.9 indicates that Norethindrone 3-(O-dimethylaminopropyl)oxime is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.1 Ų, Norethindrone 3-(O-dimethylaminopropyl)oxime exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Norethindrone 3-(O-dimethylaminopropyl)oxime has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Norethindrone 3-(O-dimethylaminopropyl)oxime?
The CAS number of Norethindrone 3-(O-dimethylaminopropyl)oxime is 66841-21-2.
What is the molecular formula of Norethindrone 3-(O-dimethylaminopropyl)oxime?
The molecular formula of Norethindrone 3-(O-dimethylaminopropyl)oxime is C25H38N2O2.
What is the molecular weight of Norethindrone 3-(O-dimethylaminopropyl)oxime?
The molecular weight of Norethindrone 3-(O-dimethylaminopropyl)oxime is 398.29 g/mol.
Where can I buy Norethindrone 3-(O-dimethylaminopropyl)oxime?
You can request a quote for Norethindrone 3-(O-dimethylaminopropyl)oxime directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Norethindrone 3-(O-dimethylaminopropyl)oxime?
Yes, KEHONG BIO provides custom synthesis services for Norethindrone 3-(O-dimethylaminopropyl)oxime and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.