O-Demethylnitidine structure

O-Demethylnitidine

TL;DR: O-Demethylnitidine (CAS 66804-22-6) is a chemical compound with molecular formula C20H16NO4+ and molecular weight 334.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-methoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium-2-ol

Also Known As: O-Demethylnitidine, Terihanine, AKNZHZBYUFSHKB-UHFFFAOYSA-, 3-methoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium-2-ol, [1,3]benzodioxolo[5,6-c]phenanthridinium, 2-hydroxy-3-methoxy-12-methyl-

CAS: 66804-22-6
Molecular Formula C20H16NO4+
Molecular Weight 334.11 g/mol
LogP 4.3
Topological Polar Surface Area 51.8 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 1
Exact Mass 334.10794
Heavy Atoms 25
Complexity 502.0

Chemical Identifiers

CAS Number 66804-22-6
SMILES C[N+]1=CC2=CC(=C(C=C2C3=C1C4=CC5=C(C=C4C=C3)OCO5)OC)O
InChIKey AKNZHZBYUFSHKB-UHFFFAOYSA-O

Product Overview

O-Demethylnitidine (CAS 66804-22-6), with molecular formula C20H16NO4+ and molecular weight 334.11 g/mol. IUPAC: 3-methoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium-2-ol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of O-Demethylnitidine

XLogP
4.3
TPSA (Topological Polar Surface Area)
51.8
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
1
Heavy Atoms
25
Complexity
502.0
Exact Mass
334.10794
Monoisotopic Mass
334.10794
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of O-Demethylnitidine

The XLogP value of 4.3 indicates that O-Demethylnitidine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.8 Ų, O-Demethylnitidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, O-Demethylnitidine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of O-Demethylnitidine?

The CAS number of O-Demethylnitidine is 66804-22-6.

What is the molecular formula of O-Demethylnitidine?

The molecular formula of O-Demethylnitidine is C20H16NO4+.

What is the molecular weight of O-Demethylnitidine?

The molecular weight of O-Demethylnitidine is 334.11 g/mol.

Where can I buy O-Demethylnitidine?

You can request a quote for O-Demethylnitidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for O-Demethylnitidine?

Yes, KEHONG BIO provides custom synthesis services for O-Demethylnitidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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