12-Methyl-18-norcholesta-8,11,13-trien-3-ol structure

12-Methyl-18-norcholesta-8,11,13-trien-3-ol

TL;DR: 12-Methyl-18-norcholesta-8,11,13-trien-3-ol (CAS 66774-44-5) is a chemical compound with molecular formula C27H44O and molecular weight 384.34 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(3S,5S,8R,17R)-10,12-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,3,4,5,6,7,8,9,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-ol

Also Known As: 12-Mncto, 12-Methyl-18-norcholesta-8,11,13-trien-3-ol, 12-Methyl-18-norcholesta-11,13-dien-3-ol, 18-Norcholesta-9,11,13-trien-3-ol, 12-methyl-, (3beta,5alpha)-, (3S,5S,8R,17R)-10,12-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,3,4,5,6,7,8,9,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-ol

CAS: 66774-44-5
Molecular Formula C27H44O
Molecular Weight 384.34 g/mol
LogP 7.3088
Topological Polar Surface Area 20.23 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 1
Rotatable Bonds 5
Exact Mass 384.3392
Heavy Atoms 28
Complexity 640.6477

Chemical Identifiers

CAS Number 66774-44-5
SMILES CC1=CC2[C@@H](CC[C@@H]3C2(CC[C@@H](C3)O)C)C4=C1[C@H](CC4)[C@H](C)CCCC(C)C

Product Overview

12-Methyl-18-norcholesta-8,11,13-trien-3-ol (CAS 66774-44-5), with molecular formula C27H44O and molecular weight 384.34 g/mol. IUPAC: (3S,5S,8R,17R)-10,12-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,3,4,5,6,7,8,9,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-ol.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 12-Methyl-18-norcholesta-8,11,13-trien-3-ol

XLogP
7.3088
TPSA (Topological Polar Surface Area)
20.23
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
1
Rotatable Bonds
5
Heavy Atoms
28
Complexity
640.6477
Exact Mass
384.3392
Monoisotopic Mass
384.3392
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 12-Methyl-18-norcholesta-8,11,13-trien-3-ol

The XLogP value of 7.3088 indicates that 12-Methyl-18-norcholesta-8,11,13-trien-3-ol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 20.23 Ų, 12-Methyl-18-norcholesta-8,11,13-trien-3-ol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 12-Methyl-18-norcholesta-8,11,13-trien-3-ol has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 12-Methyl-18-norcholesta-8,11,13-trien-3-ol?

The CAS number of 12-Methyl-18-norcholesta-8,11,13-trien-3-ol is 66774-44-5.

What is the molecular formula of 12-Methyl-18-norcholesta-8,11,13-trien-3-ol?

The molecular formula of 12-Methyl-18-norcholesta-8,11,13-trien-3-ol is C27H44O.

What is the molecular weight of 12-Methyl-18-norcholesta-8,11,13-trien-3-ol?

The molecular weight of 12-Methyl-18-norcholesta-8,11,13-trien-3-ol is 384.34 g/mol.

Where can I buy 12-Methyl-18-norcholesta-8,11,13-trien-3-ol?

You can request a quote for 12-Methyl-18-norcholesta-8,11,13-trien-3-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 12-Methyl-18-norcholesta-8,11,13-trien-3-ol?

Yes, KEHONG BIO provides custom synthesis services for 12-Methyl-18-norcholesta-8,11,13-trien-3-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

🤖 科弘生物 AI 助手 ×
您好!我是 科弘生物 AI 助手。可以问我产品搜索、询价、样品或技术问题。如何帮助您?