AH-487/41660182
TL;DR: AH-487/41660182 (CAS 664358-60-5) is a chemical compound with molecular formula C25H27FN4O2S and molecular weight 466.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-5-[(3-fluoro-4-pyrrolidin-1-ylphenyl)methylidene]-3-methyl-2-(4-morpholin-4-ylphenyl)imino-1,3-thiazolidin-4-one
Also Known As: AH-487/41660182, (5Z)-5-[(3-fluoro-4-pyrrolidin-1-ylphenyl)methylidene]-3-methyl-2-(4-morpholin-4-ylphenyl)imino-1,3-thiazolidin-4-one, (5Z)-5-[3-fluoro-4-(pyrrolidin-1-yl)benzylidene]-3-methyl-2-{[4-(morpholin-4-yl)phenyl]imino}-1,3-thiazolidin-4-one, 5-[3-fluoro-4-(1-pyrrolidinyl)benzylidene]-3-methyl-2-{[4-(4-morpholinyl)phenyl]imino}-1,3-thiazolidin-4-one
| Molecular Formula | C25H27FN4O2S |
|---|---|
| Molecular Weight | 466.18 g/mol |
| LogP | 4.4963 |
| Topological Polar Surface Area | 48.38 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 466.18387 |
| Heavy Atoms | 33 |
| Complexity | 1090.0858 |
Chemical Identifiers
| CAS Number | 664358-60-5 |
|---|---|
| SMILES | CN1C(=O)/C(=C/C2=CC(=C(C=C2)N3CCCC3)F)/SC1=NC4=CC=C(C=C4)N5CCOCC5 |
Product Overview
AH-487/41660182 (CAS 664358-60-5), with molecular formula C25H27FN4O2S and molecular weight 466.18 g/mol. IUPAC: (5Z)-5-[(3-fluoro-4-pyrrolidin-1-ylphenyl)methylidene]-3-methyl-2-(4-morpholin-4-ylphenyl)imino-1,3-thiazolidin-4-one.
Chemical Property Profile of AH-487/41660182
Property Insights of AH-487/41660182
The XLogP value of 4.4963 indicates that AH-487/41660182 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 48.38 Ų, AH-487/41660182 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AH-487/41660182 has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AH-487/41660182?
The CAS number of AH-487/41660182 is 664358-60-5.
What is the molecular formula of AH-487/41660182?
The molecular formula of AH-487/41660182 is C25H27FN4O2S.
What is the molecular weight of AH-487/41660182?
The molecular weight of AH-487/41660182 is 466.18 g/mol.
Where can I buy AH-487/41660182?
You can request a quote for AH-487/41660182 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AH-487/41660182?
Yes, KEHONG BIO provides custom synthesis services for AH-487/41660182 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.