N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide
TL;DR: N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide (CAS 664352-73-2) is a chemical compound with molecular formula C22H24ClFN2O5 and molecular weight 450.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide
Also Known As: AH-487/41184667, N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide
| Molecular Formula | C22H24ClFN2O5 |
|---|---|
| Molecular Weight | 450.14 g/mol |
| LogP | 3.9958 |
| Topological Polar Surface Area | 77.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 450.13577 |
| Heavy Atoms | 31 |
| Complexity | 951.3639 |
Chemical Identifiers
| CAS Number | 664352-73-2 |
|---|---|
| SMILES | COC1=CC(=CC(=C1OC)OC)C(=O)N2CCC(CC2)C(=O)NC3=CC(=C(C=C3)F)Cl |
Product Overview
N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide (CAS 664352-73-2), with molecular formula C22H24ClFN2O5 and molecular weight 450.14 g/mol. IUPAC: N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide.
Chemical Property Profile of N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide
Property Insights of N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide
The XLogP value of 3.9958 indicates that N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 77.1 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide. Following Lipinski's Rule of Five, N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide?
The CAS number of N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide is 664352-73-2.
What is the molecular formula of N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide?
The molecular formula of N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide is C22H24ClFN2O5.
What is the molecular weight of N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide?
The molecular weight of N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide is 450.14 g/mol.
Where can I buy N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide?
You can request a quote for N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-(3-chloro-4-fluorophenyl)-1-(3,4,5-trimethoxybenzoyl)piperidine-4-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.