8-Chloro-2-methyl-1,6-dihydro-4H-pyrimido(2,1-b)quinazolin-4-one
TL;DR: 8-Chloro-2-methyl-1,6-dihydro-4H-pyrimido(2,1-b)quinazolin-4-one (CAS 66424-86-0) is a chemical compound with molecular formula C12H10ClN3O and molecular weight 247.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-chloro-2-methyl-6,11-dihydropyrimido[2,1-b]quinazolin-4-one
Also Known As: 8-Chloro-2-methyl-1,6-dihydro-4H-pyrimido(2,1-b)quinazolin-4-one, 8-chloro-2-methyl-1,6-dihydropyrimido[2,1-b]quinazolin-4-one, 8-Chloro-2-methyl-1,6-dihydro-4H-pyrimido[2,1-b]quinazolin-4-one, 8-chloro-2-methyl-4H,6H,11H-pyrimido[2,1-b]quinazolin-4-one, 4H-Pyrimido[2,1-b]quinazolin-4-one, 8-chloro-1,6-dihydro-2-methyl-
| Molecular Formula | C12H10ClN3O |
|---|---|
| Molecular Weight | 247.05 g/mol |
| LogP | 1.4 |
| Topological Polar Surface Area | 44.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 247.05124 |
| Heavy Atoms | 17 |
| Complexity | 418.0 |
Chemical Identifiers
| CAS Number | 66424-86-0 |
|---|---|
| SMILES | CC1=CC(=O)N2CC3=C(C=CC(=C3)Cl)NC2=N1 |
| InChIKey | VNTGHFCUTLWXJS-UHFFFAOYSA-N |
Product Overview
8-Chloro-2-methyl-1,6-dihydro-4H-pyrimido(2,1-b)quinazolin-4-one (CAS 66424-86-0), with molecular formula C12H10ClN3O and molecular weight 247.05 g/mol. IUPAC: 8-chloro-2-methyl-6,11-dihydropyrimido[2,1-b]quinazolin-4-one.
Chemical Property Profile of 8-Chloro-2-methyl-1,6-dihydro-4H-pyrimido(2,1-b)quinazolin-4-one
Property Insights of 8-Chloro-2-methyl-1,6-dihydro-4H-pyrimido(2,1-b)quinazolin-4-one
The XLogP value of 1.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8-Chloro-2-methyl-1,6-dihydro-4H-pyrimido(2,1-b)quinazolin-4-one. With a topological polar surface area (TPSA) of 44.7 Ų, 8-Chloro-2-methyl-1,6-dihydro-4H-pyrimido(2,1-b)quinazolin-4-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8-Chloro-2-methyl-1,6-dihydro-4H-pyrimido(2,1-b)quinazolin-4-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-Chloro-2-methyl-1,6-dihydro-4H-pyrimido(2,1-b)quinazolin-4-one?
The CAS number of 8-Chloro-2-methyl-1,6-dihydro-4H-pyrimido(2,1-b)quinazolin-4-one is 66424-86-0.
What is the molecular formula of 8-Chloro-2-methyl-1,6-dihydro-4H-pyrimido(2,1-b)quinazolin-4-one?
The molecular formula of 8-Chloro-2-methyl-1,6-dihydro-4H-pyrimido(2,1-b)quinazolin-4-one is C12H10ClN3O.
What is the molecular weight of 8-Chloro-2-methyl-1,6-dihydro-4H-pyrimido(2,1-b)quinazolin-4-one?
The molecular weight of 8-Chloro-2-methyl-1,6-dihydro-4H-pyrimido(2,1-b)quinazolin-4-one is 247.05 g/mol.
Where can I buy 8-Chloro-2-methyl-1,6-dihydro-4H-pyrimido(2,1-b)quinazolin-4-one?
You can request a quote for 8-Chloro-2-methyl-1,6-dihydro-4H-pyrimido(2,1-b)quinazolin-4-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-Chloro-2-methyl-1,6-dihydro-4H-pyrimido(2,1-b)quinazolin-4-one?
Yes, KEHONG BIO provides custom synthesis services for 8-Chloro-2-methyl-1,6-dihydro-4H-pyrimido(2,1-b)quinazolin-4-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.