AF 14
TL;DR: AF 14 (CAS 6637-16-7) is a chemical compound with molecular formula C17H21NO and molecular weight 255.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-phenyl-1-azatricyclo[6.2.2.02,7]dodecan-5-one
Also Known As: AF 14, AF14 (antihistamine), AF14, 2H-1,4-Ethanoquinolin-6(5H)-one, hexahydro-7-phenyl-, 4-phenyl-1-azatricyclo[6.2.2.02,7]dodecan-5-one
| Molecular Formula | C17H21NO |
|---|---|
| Molecular Weight | 255.16 g/mol |
| LogP | 2.6 |
| Topological Polar Surface Area | 20.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 255.16231 |
| Heavy Atoms | 19 |
| Complexity | 352.0 |
Chemical Identifiers
| CAS Number | 6637-16-7 |
|---|---|
| SMILES | C1CN2CCC1C3C2CC(C(=O)C3)C4=CC=CC=C4 |
| InChIKey | FLBXKBCYSKRFEN-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
AF 14 (CAS 6637-16-7), with molecular formula C17H21NO and molecular weight 255.16 g/mol. IUPAC: 4-phenyl-1-azatricyclo[6.2.2.02,7]dodecan-5-one.
Chemical Property Profile of AF 14
Property Insights of AF 14
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for AF 14. With a topological polar surface area (TPSA) of 20.3 Ų, AF 14 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AF 14 has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF 14?
The CAS number of AF 14 is 6637-16-7.
What is the molecular formula of AF 14?
The molecular formula of AF 14 is C17H21NO.
What is the molecular weight of AF 14?
The molecular weight of AF 14 is 255.16 g/mol.
Where can I buy AF 14?
You can request a quote for AF 14 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF 14?
Yes, KEHONG BIO provides custom synthesis services for AF 14 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.