6-Chloro-1-methyl-4-(phenylthio)-3,4-dihydro-2(1H)-quinolinone
TL;DR: 6-Chloro-1-methyl-4-(phenylthio)-3,4-dihydro-2(1H)-quinolinone (CAS 66365-65-9) is a chemical compound with molecular formula C16H14ClNOS and molecular weight 303.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-chloro-1-methyl-4-phenylsulfanyl-3,4-dihydroquinolin-2-one
Also Known As: 6-Chloro-1-methyl-4-(phenylthio)-3,4-dihydro-2(1H)-quinolinone, 6-chloro-1-methyl-4-phenylsulfanyl-3,4-dihydroquinolin-2-one, 6-Chloro-1-methyl-4-(phenylthio)-3,4-dihydroquinolin-2(1H)-one
| Molecular Formula | C16H14ClNOS |
|---|---|
| Molecular Weight | 303.05 g/mol |
| LogP | 3.7 |
| Topological Polar Surface Area | 45.6 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 303.04846 |
| Heavy Atoms | 20 |
| Complexity | 358.0 |
Chemical Identifiers
| CAS Number | 66365-65-9 |
|---|---|
| SMILES | CN1C(=O)CC(C2=C1C=CC(=C2)Cl)SC3=CC=CC=C3 |
| InChIKey | CJWVLYIZRVMULW-UHFFFAOYSA-N |
Product Overview
6-Chloro-1-methyl-4-(phenylthio)-3,4-dihydro-2(1H)-quinolinone (CAS 66365-65-9), with molecular formula C16H14ClNOS and molecular weight 303.05 g/mol. IUPAC: 6-chloro-1-methyl-4-phenylsulfanyl-3,4-dihydroquinolin-2-one.
Chemical Property Profile of 6-Chloro-1-methyl-4-(phenylthio)-3,4-dihydro-2(1H)-quinolinone
Property Insights of 6-Chloro-1-methyl-4-(phenylthio)-3,4-dihydro-2(1H)-quinolinone
The XLogP value of 3.7 indicates that 6-Chloro-1-methyl-4-(phenylthio)-3,4-dihydro-2(1H)-quinolinone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.6 Ų, 6-Chloro-1-methyl-4-(phenylthio)-3,4-dihydro-2(1H)-quinolinone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-Chloro-1-methyl-4-(phenylthio)-3,4-dihydro-2(1H)-quinolinone has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-Chloro-1-methyl-4-(phenylthio)-3,4-dihydro-2(1H)-quinolinone?
The CAS number of 6-Chloro-1-methyl-4-(phenylthio)-3,4-dihydro-2(1H)-quinolinone is 66365-65-9.
What is the molecular formula of 6-Chloro-1-methyl-4-(phenylthio)-3,4-dihydro-2(1H)-quinolinone?
The molecular formula of 6-Chloro-1-methyl-4-(phenylthio)-3,4-dihydro-2(1H)-quinolinone is C16H14ClNOS.
What is the molecular weight of 6-Chloro-1-methyl-4-(phenylthio)-3,4-dihydro-2(1H)-quinolinone?
The molecular weight of 6-Chloro-1-methyl-4-(phenylthio)-3,4-dihydro-2(1H)-quinolinone is 303.05 g/mol.
Where can I buy 6-Chloro-1-methyl-4-(phenylthio)-3,4-dihydro-2(1H)-quinolinone?
You can request a quote for 6-Chloro-1-methyl-4-(phenylthio)-3,4-dihydro-2(1H)-quinolinone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-Chloro-1-methyl-4-(phenylthio)-3,4-dihydro-2(1H)-quinolinone?
Yes, KEHONG BIO provides custom synthesis services for 6-Chloro-1-methyl-4-(phenylthio)-3,4-dihydro-2(1H)-quinolinone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.