1-(4-Fluorobenzyl)-5-oxoproline structure

1-(4-Fluorobenzyl)-5-oxoproline

TL;DR: 1-(4-Fluorobenzyl)-5-oxoproline (CAS 66183-72-0) is a chemical compound with molecular formula C12H12FNO3 and molecular weight 237.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-[(4-fluorophenyl)methyl]-5-oxopyrrolidine-2-carboxylic acid

Also Known As: 1-(4-fluorobenzyl)-5-oxoproline, ChemDiv2_003417, Proline, 1-[(4-fluorophenyl)methyl]-5-oxo-, 1-(4-Fluorobenzyl)-5-oxopyrrolidine-2-carboxylic acid, 1-[(4-fluorophenyl)methyl]-5-oxopyrrolidine-2-carboxylic acid

CAS: 66183-72-0
Molecular Formula C12H12FNO3
Molecular Weight 237.08 g/mol
LogP 1.4013
Topological Polar Surface Area 57.61 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 3
Exact Mass 237.08012
Heavy Atoms 17
Complexity 443.56888

Chemical Identifiers

CAS Number 66183-72-0
SMILES C1CC(=O)N(C1C(=O)O)CC2=CC=C(C=C2)F

Product Overview

1-(4-Fluorobenzyl)-5-oxoproline (CAS 66183-72-0), with molecular formula C12H12FNO3 and molecular weight 237.08 g/mol. IUPAC: 1-[(4-fluorophenyl)methyl]-5-oxopyrrolidine-2-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 1-(4-Fluorobenzyl)-5-oxoproline

XLogP
1.4013
TPSA (Topological Polar Surface Area)
57.61
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
3
Heavy Atoms
17
Complexity
443.56888
Exact Mass
237.08012
Monoisotopic Mass
237.08012
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 1-(4-Fluorobenzyl)-5-oxoproline

The XLogP value of 1.4013 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(4-Fluorobenzyl)-5-oxoproline. With a topological polar surface area (TPSA) of 57.61 Ų, 1-(4-Fluorobenzyl)-5-oxoproline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(4-Fluorobenzyl)-5-oxoproline has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 1-(4-Fluorobenzyl)-5-oxoproline?

The CAS number of 1-(4-Fluorobenzyl)-5-oxoproline is 66183-72-0.

What is the molecular formula of 1-(4-Fluorobenzyl)-5-oxoproline?

The molecular formula of 1-(4-Fluorobenzyl)-5-oxoproline is C12H12FNO3.

What is the molecular weight of 1-(4-Fluorobenzyl)-5-oxoproline?

The molecular weight of 1-(4-Fluorobenzyl)-5-oxoproline is 237.08 g/mol.

Where can I buy 1-(4-Fluorobenzyl)-5-oxoproline?

You can request a quote for 1-(4-Fluorobenzyl)-5-oxoproline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 1-(4-Fluorobenzyl)-5-oxoproline?

Yes, KEHONG BIO provides custom synthesis services for 1-(4-Fluorobenzyl)-5-oxoproline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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