GW843682X
TL;DR: GW843682X (CAS 660868-91-7) is a chemical compound with molecular formula C22H18F3N3O4S and molecular weight 477.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(5,6-dimethoxybenzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]thiophene-2-carboxamide
Also Known As: DBTBOT-carboxamide, Plk Inhibitor III, thiophene deriv.,20, thiophene deriv., 20, BMCL191018 Compound 2
| Molecular Formula | C22H18F3N3O4S |
|---|---|
| Molecular Weight | 477.10 g/mol |
| LogP | 4.8009 |
| Topological Polar Surface Area | 88.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 477.09702 |
| Heavy Atoms | 33 |
| Complexity | 1330.4126 |
Chemical Identifiers
| CAS Number | 660868-91-7 |
|---|---|
| SMILES | COC1=C(C=C2C(=C1)N=CN2C3=CC(=C(S3)C(=O)N)OCC4=CC=CC=C4C(F)(F)F)OC |
Product Overview
GW843682X (CAS 660868-91-7), with molecular formula C22H18F3N3O4S and molecular weight 477.10 g/mol. IUPAC: 5-(5,6-dimethoxybenzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]thiophene-2-carboxamide.
Chemical Property Profile of GW843682X
Property Insights of GW843682X
The XLogP value of 4.8009 indicates that GW843682X is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 88.6 Ų falls within the moderate polarity range, balancing permeability and solubility for GW843682X. Following Lipinski's Rule of Five, GW843682X has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of GW843682X?
The CAS number of GW843682X is 660868-91-7.
What is the molecular formula of GW843682X?
The molecular formula of GW843682X is C22H18F3N3O4S.
What is the molecular weight of GW843682X?
The molecular weight of GW843682X is 477.10 g/mol.
Where can I buy GW843682X?
You can request a quote for GW843682X directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for GW843682X?
Yes, KEHONG BIO provides custom synthesis services for GW843682X and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.