Di-tert-butyl 2-butynedioate structure

Di-tert-butyl 2-butynedioate

TL;DR: Di-tert-butyl 2-butynedioate (CAS 66086-33-7) is a chemical compound with molecular formula C12H18O4 and molecular weight 226.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ditert-butyl but-2-ynedioate

Also Known As: di-tert-Butyl acetylenedicarboxylate, ditert-butyl but-2-ynedioate, Di-tert-butyl 2-butynedioate, Di-tert-butyl but-2-ynedioate, Di-tert-butyl butynedioate

CAS: 66086-33-7
Molecular Formula C12H18O4
Molecular Weight 226.12 g/mol
LogP 2.8
Topological Polar Surface Area 52.6 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 4
Exact Mass 226.12051
Heavy Atoms 16
Complexity 309.0

Chemical Identifiers

CAS Number 66086-33-7
SMILES CC(C)(C)OC(=O)C#CC(=O)OC(C)(C)C
InChIKey FBCRUXRGQFLOMC-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 6 IPC patent classification(s) across the SureChEMBL global patent database.

Coatings & Adhesives (1 patents) Electronic Chemicals (1 patents) Heterocyclic Building Blocks (16 patents) Peptides & Amino Acids (1 patents) Pharmaceutical Intermediates (16 patents) +1 more

Product Overview

Di-tert-butyl 2-butynedioate (CAS 66086-33-7), with molecular formula C12H18O4 and molecular weight 226.12 g/mol. IUPAC: ditert-butyl but-2-ynedioate.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Di-tert-butyl 2-butynedioate

XLogP
2.8
TPSA (Topological Polar Surface Area)
52.6
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
4
Heavy Atoms
16
Complexity
309.0
Exact Mass
226.12051
Monoisotopic Mass
226.12051
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Di-tert-butyl 2-butynedioate

The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Di-tert-butyl 2-butynedioate. With a topological polar surface area (TPSA) of 52.6 Ų, Di-tert-butyl 2-butynedioate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Di-tert-butyl 2-butynedioate has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Di-tert-butyl 2-butynedioate?

The CAS number of Di-tert-butyl 2-butynedioate is 66086-33-7.

What is the molecular formula of Di-tert-butyl 2-butynedioate?

The molecular formula of Di-tert-butyl 2-butynedioate is C12H18O4.

What is the molecular weight of Di-tert-butyl 2-butynedioate?

The molecular weight of Di-tert-butyl 2-butynedioate is 226.12 g/mol.

Where can I buy Di-tert-butyl 2-butynedioate?

You can request a quote for Di-tert-butyl 2-butynedioate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Di-tert-butyl 2-butynedioate?

Yes, KEHONG BIO provides custom synthesis services for Di-tert-butyl 2-butynedioate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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