1-(trans-4-Hydroxytetrahydro-2-furanyl)-5-fluorouracil
TL;DR: 1-(trans-4-Hydroxytetrahydro-2-furanyl)-5-fluorouracil (CAS 66067-15-0) is a chemical compound with molecular formula C8H9FN2O4 and molecular weight 216.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-fluoro-1-(4-hydroxyoxolan-2-yl)pyrimidine-2,4-dione
Also Known As: Pinane-thromboxane A2, cis-1-[4-hydroxytetrahydro-2-furyl]-5-fluorouracil, 5-Fluoro-1-[(4-hydroxytetrahydrofuran)-2-yl]uracil, 1-(trans-4-Hydroxytetrahydro-2-furanyl)-5-fluorouracil, 5-fluoro-1-(4-hydroxyoxolan-2-yl)pyrimidine-2,4-dione
| Molecular Formula | C8H9FN2O4 |
|---|---|
| Molecular Weight | 216.05 g/mol |
| LogP | -1.2 |
| Topological Polar Surface Area | 78.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 216.05464 |
| Heavy Atoms | 15 |
| Complexity | 344.0 |
Chemical Identifiers
| CAS Number | 66067-15-0 |
|---|---|
| SMILES | C1C(COC1N2C=C(C(=O)NC2=O)F)O |
| InChIKey | PYMAPGFRXCXQCU-UHFFFAOYSA-N |
Product Overview
1-(trans-4-Hydroxytetrahydro-2-furanyl)-5-fluorouracil (CAS 66067-15-0), with molecular formula C8H9FN2O4 and molecular weight 216.05 g/mol. IUPAC: 5-fluoro-1-(4-hydroxyoxolan-2-yl)pyrimidine-2,4-dione.
Chemical Property Profile of 1-(trans-4-Hydroxytetrahydro-2-furanyl)-5-fluorouracil
Property Insights of 1-(trans-4-Hydroxytetrahydro-2-furanyl)-5-fluorouracil
The XLogP value of -1.2 indicates that 1-(trans-4-Hydroxytetrahydro-2-furanyl)-5-fluorouracil is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 78.9 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(trans-4-Hydroxytetrahydro-2-furanyl)-5-fluorouracil. Following Lipinski's Rule of Five, 1-(trans-4-Hydroxytetrahydro-2-furanyl)-5-fluorouracil has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(trans-4-Hydroxytetrahydro-2-furanyl)-5-fluorouracil?
The CAS number of 1-(trans-4-Hydroxytetrahydro-2-furanyl)-5-fluorouracil is 66067-15-0.
What is the molecular formula of 1-(trans-4-Hydroxytetrahydro-2-furanyl)-5-fluorouracil?
The molecular formula of 1-(trans-4-Hydroxytetrahydro-2-furanyl)-5-fluorouracil is C8H9FN2O4.
What is the molecular weight of 1-(trans-4-Hydroxytetrahydro-2-furanyl)-5-fluorouracil?
The molecular weight of 1-(trans-4-Hydroxytetrahydro-2-furanyl)-5-fluorouracil is 216.05 g/mol.
Where can I buy 1-(trans-4-Hydroxytetrahydro-2-furanyl)-5-fluorouracil?
You can request a quote for 1-(trans-4-Hydroxytetrahydro-2-furanyl)-5-fluorouracil directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(trans-4-Hydroxytetrahydro-2-furanyl)-5-fluorouracil?
Yes, KEHONG BIO provides custom synthesis services for 1-(trans-4-Hydroxytetrahydro-2-furanyl)-5-fluorouracil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.