Trifluoroacetyl melatonin structure

Trifluoroacetyl melatonin

TL;DR: Trifluoroacetyl melatonin (CAS 66012-91-7) is a chemical compound with molecular formula C15H13F3N2O2 and molecular weight 310.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2,2,2-trifluoro-1-(5-methoxy-2'-methylidenespiro[indole-3,3'-pyrrolidine]-1'-yl)ethanone

Also Known As: Trifluoroacetyl melatonin, Melatonin TFA (spiro(3H-indole-3,3'-pyrrolidine) form), 5-METHOXYINDOLE-3-SPIRO-3'-N-TRIFLUOROACETYL-2'-METHYLENEPYRROLIDINE, 1 -(Trifluoroacetyl)-5-methoxy-2 -methylenespiro[3H-indole-3,3 -pyrrolidine], 2,2,2-trifluoro-1-(5-methoxy-2'-methylidenespiro[indole-3,3'-pyrrolidine]-1'-yl)ethanone

CAS: 66012-91-7
Molecular Formula C15H13F3N2O2
Molecular Weight 310.09 g/mol
LogP 2.1
Topological Polar Surface Area 41.9 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 6
Rotatable Bonds 1
Exact Mass 310.09293
Heavy Atoms 22
Complexity 531.0

Chemical Identifiers

CAS Number 66012-91-7
SMILES COC1=CC2=C(C=C1)N=CC23CCN(C3=C)C(=O)C(F)(F)F
InChIKey RAEVVXJFQROQDJ-UHFFFAOYSA-N

Product Overview

Trifluoroacetyl melatonin (CAS 66012-91-7), with molecular formula C15H13F3N2O2 and molecular weight 310.09 g/mol. IUPAC: 2,2,2-trifluoro-1-(5-methoxy-2'-methylidenespiro[indole-3,3'-pyrrolidine]-1'-yl)ethanone.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Trifluoroacetyl melatonin

XLogP
2.1
TPSA (Topological Polar Surface Area)
41.9
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
6
Rotatable Bonds
1
Heavy Atoms
22
Complexity
531.0
Exact Mass
310.09293
Monoisotopic Mass
310.09293
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Trifluoroacetyl melatonin

The XLogP value of 2.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Trifluoroacetyl melatonin. With a topological polar surface area (TPSA) of 41.9 Ų, Trifluoroacetyl melatonin exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Trifluoroacetyl melatonin has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Trifluoroacetyl melatonin?

The CAS number of Trifluoroacetyl melatonin is 66012-91-7.

What is the molecular formula of Trifluoroacetyl melatonin?

The molecular formula of Trifluoroacetyl melatonin is C15H13F3N2O2.

What is the molecular weight of Trifluoroacetyl melatonin?

The molecular weight of Trifluoroacetyl melatonin is 310.09 g/mol.

Where can I buy Trifluoroacetyl melatonin?

You can request a quote for Trifluoroacetyl melatonin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Trifluoroacetyl melatonin?

Yes, KEHONG BIO provides custom synthesis services for Trifluoroacetyl melatonin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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