NSC 26480 (5,6-dihydro-5-azacytidine)
TL;DR: NSC 26480 (5,6-dihydro-5-azacytidine) (CAS 65886-72-8) is a chemical compound with molecular formula C8H15ClN4O5 and molecular weight 282.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-amino-3-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,4-dihydro-1,3,5-triazin-2-one;hydrochloride
Also Known As: dhac hydrochloride, DHAC, Dihydro-5-azacytidine, H5AC HCl, 5-ACH
| Molecular Formula | C8H15ClN4O5 |
|---|---|
| Molecular Weight | 282.07 g/mol |
| LogP | -2.8554 |
| Topological Polar Surface Area | 140.64 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 2 |
| Exact Mass | 282.0731 |
| Heavy Atoms | 18 |
| Complexity | 354.37903 |
Chemical Identifiers
| CAS Number | 65886-72-8 |
|---|---|
| SMILES | C1N=C(NC(=O)N1C2C(C(C(O2)CO)O)O)N.Cl |
Product Overview
NSC 26480 (5,6-dihydro-5-azacytidine) (CAS 65886-72-8), with molecular formula C8H15ClN4O5 and molecular weight 282.07 g/mol. IUPAC: 6-amino-3-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,4-dihydro-1,3,5-triazin-2-one;hydrochloride.
Chemical Property Profile of NSC 26480 (5,6-dihydro-5-azacytidine)
Property Insights of NSC 26480 (5,6-dihydro-5-azacytidine)
The XLogP value of -2.8554 indicates that NSC 26480 (5,6-dihydro-5-azacytidine) is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 140.64 Ų indicates high polarity, suggesting NSC 26480 (5,6-dihydro-5-azacytidine) may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, NSC 26480 (5,6-dihydro-5-azacytidine) has 5 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of NSC 26480 (5,6-dihydro-5-azacytidine)?
The CAS number of NSC 26480 (5,6-dihydro-5-azacytidine) is 65886-72-8.
What is the molecular formula of NSC 26480 (5,6-dihydro-5-azacytidine)?
The molecular formula of NSC 26480 (5,6-dihydro-5-azacytidine) is C8H15ClN4O5.
What is the molecular weight of NSC 26480 (5,6-dihydro-5-azacytidine)?
The molecular weight of NSC 26480 (5,6-dihydro-5-azacytidine) is 282.07 g/mol.
Where can I buy NSC 26480 (5,6-dihydro-5-azacytidine)?
You can request a quote for NSC 26480 (5,6-dihydro-5-azacytidine) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for NSC 26480 (5,6-dihydro-5-azacytidine)?
Yes, KEHONG BIO provides custom synthesis services for NSC 26480 (5,6-dihydro-5-azacytidine) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.