Fazarabine
TL;DR: Fazarabine (CAS 65886-71-7) is a chemical compound with molecular formula C8H12N4O5 and molecular weight 244.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
Also Known As: Fazarabina, Ara-AC, Fazarabinum, Kymarabine, 5-Azacytosine arabinoside
| Molecular Formula | C8H12N4O5 |
|---|---|
| Molecular Weight | 244.08 g/mol |
| LogP | -2.2 |
| Topological Polar Surface Area | 141.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 244.08076 |
| Heavy Atoms | 17 |
| Complexity | 384.0 |
| Solubility | Water > 16 (mg/mL) |
Chemical Identifiers
| CAS Number | 65886-71-7 |
|---|---|
| SMILES | C1=NC(=NC(=O)N1[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O)N |
| InChIKey | NMUSYJAQQFHJEW-ARQDHWQXSA-N |
Patent-Derived Application Labels
Derived from 10 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Fazarabine (CAS 65886-71-7), with molecular formula C8H12N4O5 and molecular weight 244.08 g/mol. IUPAC: 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one.
Chemical Property Profile of Fazarabine
Property Insights of Fazarabine
The XLogP value of -2.2 indicates that Fazarabine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 141.0 Ų indicates high polarity, suggesting Fazarabine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Fazarabine has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Fazarabine?
The CAS number of Fazarabine is 65886-71-7.
What is the molecular formula of Fazarabine?
The molecular formula of Fazarabine is C8H12N4O5.
What is the molecular weight of Fazarabine?
The molecular weight of Fazarabine is 244.08 g/mol.
Where can I buy Fazarabine?
You can request a quote for Fazarabine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Fazarabine?
Yes, KEHONG BIO provides custom synthesis services for Fazarabine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.