(E)-N-(4-acetamidophenyl)-3-(thiophen-2-yl)acrylamide
TL;DR: (E)-N-(4-acetamidophenyl)-3-(thiophen-2-yl)acrylamide (CAS 658069-99-9) is a chemical compound with molecular formula C15H14N2O2S and molecular weight 286.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-(4-acetamidophenyl)-3-thiophen-2-ylprop-2-enamide
Also Known As: (E)-N-(4-acetamidophenyl)-3-(thiophen-2-yl)acrylamide, (E)-N-(4-acetamidophenyl)-3-thiophen-2-ylprop-2-enamide, (2E)-N-(4-ACETAMIDOPHENYL)-3-(THIOPHEN-2-YL)PROP-2-ENAMIDE, F1736-0629, (2E)-N-[4-(acetylamino)phenyl]-3-(2-thienyl)prop-2-enamide
| Molecular Formula | C15H14N2O2S |
|---|---|
| Molecular Weight | 286.08 g/mol |
| LogP | 3.3584 |
| Topological Polar Surface Area | 58.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 286.0776 |
| Heavy Atoms | 20 |
| Complexity | 615.8329 |
Chemical Identifiers
| CAS Number | 658069-99-9 |
|---|---|
| SMILES | CC(=O)NC1=CC=C(C=C1)NC(=O)/C=C/C2=CC=CS2 |
Product Overview
(E)-N-(4-acetamidophenyl)-3-(thiophen-2-yl)acrylamide (CAS 658069-99-9), with molecular formula C15H14N2O2S and molecular weight 286.08 g/mol. IUPAC: (E)-N-(4-acetamidophenyl)-3-thiophen-2-ylprop-2-enamide.
Chemical Property Profile of (E)-N-(4-acetamidophenyl)-3-(thiophen-2-yl)acrylamide
Property Insights of (E)-N-(4-acetamidophenyl)-3-(thiophen-2-yl)acrylamide
The XLogP value of 3.3584 indicates that (E)-N-(4-acetamidophenyl)-3-(thiophen-2-yl)acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.2 Ų, (E)-N-(4-acetamidophenyl)-3-(thiophen-2-yl)acrylamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-N-(4-acetamidophenyl)-3-(thiophen-2-yl)acrylamide has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N-(4-acetamidophenyl)-3-(thiophen-2-yl)acrylamide?
The CAS number of (E)-N-(4-acetamidophenyl)-3-(thiophen-2-yl)acrylamide is 658069-99-9.
What is the molecular formula of (E)-N-(4-acetamidophenyl)-3-(thiophen-2-yl)acrylamide?
The molecular formula of (E)-N-(4-acetamidophenyl)-3-(thiophen-2-yl)acrylamide is C15H14N2O2S.
What is the molecular weight of (E)-N-(4-acetamidophenyl)-3-(thiophen-2-yl)acrylamide?
The molecular weight of (E)-N-(4-acetamidophenyl)-3-(thiophen-2-yl)acrylamide is 286.08 g/mol.
Where can I buy (E)-N-(4-acetamidophenyl)-3-(thiophen-2-yl)acrylamide?
You can request a quote for (E)-N-(4-acetamidophenyl)-3-(thiophen-2-yl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N-(4-acetamidophenyl)-3-(thiophen-2-yl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N-(4-acetamidophenyl)-3-(thiophen-2-yl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.