3-Hydroxyproquazone
TL;DR: 3-Hydroxyproquazone (CAS 65765-07-3) is a chemical compound with molecular formula C18H18N2O2 and molecular weight 294.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(3-hydroxyphenyl)-7-methyl-1-propan-2-ylquinazolin-2-one
Also Known As: 3-Hydroxyproquazone, meta-Hydroxyproquazone, Compound 50-892, 4-(3-hydroxyphenyl)-7-methyl-1-propan-2-ylquinazolin-2-one, J2.504.553J
| Molecular Formula | C18H18N2O2 |
|---|---|
| Molecular Weight | 294.14 g/mol |
| LogP | 3.7 |
| Topological Polar Surface Area | 52.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 294.13684 |
| Heavy Atoms | 22 |
| Complexity | 460.0 |
Chemical Identifiers
| CAS Number | 65765-07-3 |
|---|---|
| SMILES | CC1=CC2=C(C=C1)C(=NC(=O)N2C(C)C)C3=CC(=CC=C3)O |
| InChIKey | HGZHAINHFBFXIU-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
3-Hydroxyproquazone (CAS 65765-07-3), with molecular formula C18H18N2O2 and molecular weight 294.14 g/mol. IUPAC: 4-(3-hydroxyphenyl)-7-methyl-1-propan-2-ylquinazolin-2-one.
Chemical Property Profile of 3-Hydroxyproquazone
Property Insights of 3-Hydroxyproquazone
The XLogP value of 3.7 indicates that 3-Hydroxyproquazone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 52.9 Ų, 3-Hydroxyproquazone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-Hydroxyproquazone has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-Hydroxyproquazone?
The CAS number of 3-Hydroxyproquazone is 65765-07-3.
What is the molecular formula of 3-Hydroxyproquazone?
The molecular formula of 3-Hydroxyproquazone is C18H18N2O2.
What is the molecular weight of 3-Hydroxyproquazone?
The molecular weight of 3-Hydroxyproquazone is 294.14 g/mol.
Where can I buy 3-Hydroxyproquazone?
You can request a quote for 3-Hydroxyproquazone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-Hydroxyproquazone?
Yes, KEHONG BIO provides custom synthesis services for 3-Hydroxyproquazone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.