d-Naloxone
TL;DR: d-Naloxone (CAS 65700-73-4) is a chemical compound with molecular formula C19H21NO4 and molecular weight 327.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4S,4aR,7aS,12bR)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
Also Known As: d-Naloxone, (+)-naloxone, naloxone, Naloxone, (+)-, PDSP2_001521
| Molecular Formula | C19H21NO4 |
|---|---|
| Molecular Weight | 327.15 g/mol |
| LogP | 1.3014 |
| Topological Polar Surface Area | 70.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 327.14706 |
| Heavy Atoms | 24 |
| Complexity | 774.8754 |
Chemical Identifiers
| CAS Number | 65700-73-4 |
|---|---|
| SMILES | C=CCN1CC[C@@]23[C@H]4C(=O)CC[C@@]2([C@@H]1CC5=C3C(=C(C=C5)O)O4)O |
Product Overview
d-Naloxone (CAS 65700-73-4), with molecular formula C19H21NO4 and molecular weight 327.15 g/mol. IUPAC: (4S,4aR,7aS,12bR)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one.
Chemical Property Profile of d-Naloxone
Property Insights of d-Naloxone
The XLogP value of 1.3014 suggests moderate lipophilicity, balancing water solubility and membrane permeability for d-Naloxone. The TPSA of 70.0 Ų falls within the moderate polarity range, balancing permeability and solubility for d-Naloxone. Following Lipinski's Rule of Five, d-Naloxone has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of d-Naloxone?
The CAS number of d-Naloxone is 65700-73-4.
What is the molecular formula of d-Naloxone?
The molecular formula of d-Naloxone is C19H21NO4.
What is the molecular weight of d-Naloxone?
The molecular weight of d-Naloxone is 327.15 g/mol.
Where can I buy d-Naloxone?
You can request a quote for d-Naloxone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for d-Naloxone?
Yes, KEHONG BIO provides custom synthesis services for d-Naloxone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.