Asenapine
TL;DR: Asenapine (CAS 65576-39-8) is a chemical compound with molecular formula C17H16ClNO and molecular weight 285.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R,6R)-9-chloro-4-methyl-13-oxa-4-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaene
Also Known As: Asenapine, Saphris, (R,R)-asenapine, Asenapine free base, Asenapine maleate
| Molecular Formula | C17H16ClNO |
|---|---|
| Molecular Weight | 285.09 g/mol |
| LogP | 4.2585 |
| Topological Polar Surface Area | 12.47 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 285.09204 |
| Heavy Atoms | 20 |
| Complexity | 669.7896 |
Chemical Identifiers
| CAS Number | 65576-39-8 |
|---|---|
| SMILES | CN1C[C@@H]2[C@@H](C1)C3=C(C=CC(=C3)Cl)OC4=CC=CC=C24 |
Product Overview
Asenapine (CAS 65576-39-8), with molecular formula C17H16ClNO and molecular weight 285.09 g/mol. IUPAC: (2R,6R)-9-chloro-4-methyl-13-oxa-4-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7(12),8,10,14,16-hexaene.
Chemical Property Profile of Asenapine
Property Insights of Asenapine
The XLogP value of 4.2585 indicates that Asenapine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.47 Ų, Asenapine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Asenapine has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Asenapine?
The CAS number of Asenapine is 65576-39-8.
What is the molecular formula of Asenapine?
The molecular formula of Asenapine is C17H16ClNO.
What is the molecular weight of Asenapine?
The molecular weight of Asenapine is 285.09 g/mol.
Where can I buy Asenapine?
You can request a quote for Asenapine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Asenapine?
Yes, KEHONG BIO provides custom synthesis services for Asenapine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.