Lofemizole
TL;DR: Lofemizole (CAS 65571-68-8) is a chemical compound with molecular formula C10H9ClN2 and molecular weight 192.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(4-chlorophenyl)-5-methyl-1H-imidazole
Also Known As: Lofemizole, Lofemizol, Lofemizolum, 4-(4-chlorophenyl)-5-methyl-1h-imidazole, Lofemizole [INN]
| Molecular Formula | C10H9ClN2 |
|---|---|
| Molecular Weight | 192.05 g/mol |
| LogP | 2.8 |
| Topological Polar Surface Area | 28.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 192.04543 |
| Heavy Atoms | 13 |
| Complexity | 166.0 |
Chemical Identifiers
| CAS Number | 65571-68-8 |
|---|---|
| SMILES | CC1=C(N=CN1)C2=CC=C(C=C2)Cl |
| InChIKey | MBKWNJVQSFBLQI-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 8 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Lofemizole (CAS 65571-68-8), with molecular formula C10H9ClN2 and molecular weight 192.05 g/mol. IUPAC: 4-(4-chlorophenyl)-5-methyl-1H-imidazole.
Chemical Property Profile of Lofemizole
Property Insights of Lofemizole
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Lofemizole. With a topological polar surface area (TPSA) of 28.7 Ų, Lofemizole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Lofemizole has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Lofemizole?
The CAS number of Lofemizole is 65571-68-8.
What is the molecular formula of Lofemizole?
The molecular formula of Lofemizole is C10H9ClN2.
What is the molecular weight of Lofemizole?
The molecular weight of Lofemizole is 192.05 g/mol.
Where can I buy Lofemizole?
You can request a quote for Lofemizole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Lofemizole?
Yes, KEHONG BIO provides custom synthesis services for Lofemizole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.