2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)-1-(thiophen-2-yl)ethanone structure

2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)-1-(thiophen-2-yl)ethanone

TL;DR: 2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)-1-(thiophen-2-yl)ethanone (CAS 654635-98-0) is a chemical compound with molecular formula C20H18N2OS2 and molecular weight 366.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[(2-phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)sulfanyl]-1-thiophen-2-ylethanone

Also Known As: F1411-0269, AP-048/41435287, 2-((2-phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)-1-(thiophen-2-yl)ethanone, 2-[(2-phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)sulfanyl]-1-(thiophen-2-yl)ethan-1-one, 2-[(2-phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)sulfanyl]-1-thiophen-2-ylethanone

CAS: 654635-98-0
Molecular Formula C20H18N2OS2
Molecular Weight 366.09 g/mol
LogP 5.0589
Topological Polar Surface Area 42.85 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 5
Rotatable Bonds 5
Exact Mass 366.08606
Heavy Atoms 25
Complexity 876.2216

Chemical Identifiers

CAS Number 654635-98-0
SMILES C1CCC2=C(C1)C(=NC(=N2)C3=CC=CC=C3)SCC(=O)C4=CC=CS4

Product Overview

2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)-1-(thiophen-2-yl)ethanone (CAS 654635-98-0), with molecular formula C20H18N2OS2 and molecular weight 366.09 g/mol. IUPAC: 2-[(2-phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)sulfanyl]-1-thiophen-2-ylethanone.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)-1-(thiophen-2-yl)ethanone

XLogP
5.0589
TPSA (Topological Polar Surface Area)
42.85
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
5
Rotatable Bonds
5
Heavy Atoms
25
Complexity
876.2216
Exact Mass
366.08606
Monoisotopic Mass
366.08606
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)-1-(thiophen-2-yl)ethanone

The XLogP value of 5.0589 indicates that 2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)-1-(thiophen-2-yl)ethanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 42.85 Ų, 2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)-1-(thiophen-2-yl)ethanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)-1-(thiophen-2-yl)ethanone has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)-1-(thiophen-2-yl)ethanone?

The CAS number of 2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)-1-(thiophen-2-yl)ethanone is 654635-98-0.

What is the molecular formula of 2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)-1-(thiophen-2-yl)ethanone?

The molecular formula of 2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)-1-(thiophen-2-yl)ethanone is C20H18N2OS2.

What is the molecular weight of 2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)-1-(thiophen-2-yl)ethanone?

The molecular weight of 2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)-1-(thiophen-2-yl)ethanone is 366.09 g/mol.

Where can I buy 2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)-1-(thiophen-2-yl)ethanone?

You can request a quote for 2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)-1-(thiophen-2-yl)ethanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)-1-(thiophen-2-yl)ethanone?

Yes, KEHONG BIO provides custom synthesis services for 2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)-1-(thiophen-2-yl)ethanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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