Fluticasone propionate-17beta-carboxylic acid
TL;DR: Fluticasone propionate-17beta-carboxylic acid (CAS 65429-42-7) is a chemical compound with molecular formula C24H30F2O6 and molecular weight 452.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carboxylic acid
Also Known As: FP17betaCA, Fluticasone Impurity A, Fluticasone propionate-17beta-carboxylic acid, Fluticasone EP Impurity A, Fluticasone 17b-carboxylic acid propionate
| Molecular Formula | C24H30F2O6 |
|---|---|
| Molecular Weight | 452.20 g/mol |
| LogP | 3.3278 |
| Topological Polar Surface Area | 100.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 452.20105 |
| Heavy Atoms | 32 |
| Complexity | 944.7739 |
Chemical Identifiers
| CAS Number | 65429-42-7 |
|---|---|
| SMILES | CCC(=O)O[C@@]1([C@@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2C[C@@H](C4=CC(=O)C=C[C@@]43C)F)F)O)C)C)C(=O)O |
Product Overview
Fluticasone propionate-17beta-carboxylic acid (CAS 65429-42-7), with molecular formula C24H30F2O6 and molecular weight 452.20 g/mol. IUPAC: (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carboxylic acid.
Chemical Property Profile of Fluticasone propionate-17beta-carboxylic acid
Property Insights of Fluticasone propionate-17beta-carboxylic acid
The XLogP value of 3.3278 indicates that Fluticasone propionate-17beta-carboxylic acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 100.9 Ų falls within the moderate polarity range, balancing permeability and solubility for Fluticasone propionate-17beta-carboxylic acid. Following Lipinski's Rule of Five, Fluticasone propionate-17beta-carboxylic acid has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Fluticasone propionate-17beta-carboxylic acid?
The CAS number of Fluticasone propionate-17beta-carboxylic acid is 65429-42-7.
What is the molecular formula of Fluticasone propionate-17beta-carboxylic acid?
The molecular formula of Fluticasone propionate-17beta-carboxylic acid is C24H30F2O6.
What is the molecular weight of Fluticasone propionate-17beta-carboxylic acid?
The molecular weight of Fluticasone propionate-17beta-carboxylic acid is 452.20 g/mol.
Where can I buy Fluticasone propionate-17beta-carboxylic acid?
You can request a quote for Fluticasone propionate-17beta-carboxylic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Fluticasone propionate-17beta-carboxylic acid?
Yes, KEHONG BIO provides custom synthesis services for Fluticasone propionate-17beta-carboxylic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.