4-Fluoro-2-(trifluoromethyl)cinnamic acid structure

4-Fluoro-2-(trifluoromethyl)cinnamic acid

TL;DR: 4-Fluoro-2-(trifluoromethyl)cinnamic acid (CAS 654-95-5) is a chemical compound with molecular formula C10H6F4O2 and molecular weight 234.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(E)-3-[4-fluoro-2-(trifluoromethyl)phenyl]prop-2-enoic acid

Also Known As: 4-Fluoro-2-(trifluoromethyl)cinnamic acid, 2,3,5-Trichlorobiphenyl, 4-FLUORO-2- CINNAMICACID, 3-[4-fluoro-2-(trifluoromethyl)phenyl]prop-2-enoic Acid, (E)-3-[4-fluoro-2-(trifluoromethyl)phenyl]prop-2-enoic acid

CAS: 654-95-5
Molecular Formula C10H6F4O2
Molecular Weight 234.03 g/mol
LogP 2.9423
Topological Polar Surface Area 37.3 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 1
Rotatable Bonds 2
Exact Mass 234.0304
Heavy Atoms 16
Complexity 434.93542

Chemical Identifiers

CAS Number 654-95-5
SMILES C1=CC(=C(C=C1F)C(F)(F)F)/C=C/C(=O)O

Product Overview

4-Fluoro-2-(trifluoromethyl)cinnamic acid (CAS 654-95-5), with molecular formula C10H6F4O2 and molecular weight 234.03 g/mol. IUPAC: (E)-3-[4-fluoro-2-(trifluoromethyl)phenyl]prop-2-enoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 4-Fluoro-2-(trifluoromethyl)cinnamic acid

XLogP
2.9423
TPSA (Topological Polar Surface Area)
37.3
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
1
Rotatable Bonds
2
Heavy Atoms
16
Complexity
434.93542
Exact Mass
234.0304
Monoisotopic Mass
234.0304
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4-Fluoro-2-(trifluoromethyl)cinnamic acid

The XLogP value of 2.9423 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Fluoro-2-(trifluoromethyl)cinnamic acid. With a topological polar surface area (TPSA) of 37.3 Ų, 4-Fluoro-2-(trifluoromethyl)cinnamic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Fluoro-2-(trifluoromethyl)cinnamic acid has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4-Fluoro-2-(trifluoromethyl)cinnamic acid?

The CAS number of 4-Fluoro-2-(trifluoromethyl)cinnamic acid is 654-95-5.

What is the molecular formula of 4-Fluoro-2-(trifluoromethyl)cinnamic acid?

The molecular formula of 4-Fluoro-2-(trifluoromethyl)cinnamic acid is C10H6F4O2.

What is the molecular weight of 4-Fluoro-2-(trifluoromethyl)cinnamic acid?

The molecular weight of 4-Fluoro-2-(trifluoromethyl)cinnamic acid is 234.03 g/mol.

Where can I buy 4-Fluoro-2-(trifluoromethyl)cinnamic acid?

You can request a quote for 4-Fluoro-2-(trifluoromethyl)cinnamic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4-Fluoro-2-(trifluoromethyl)cinnamic acid?

Yes, KEHONG BIO provides custom synthesis services for 4-Fluoro-2-(trifluoromethyl)cinnamic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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