4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide structure

4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide

TL;DR: 4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide (CAS 654-62-6) is a chemical compound with molecular formula C7H8F3N3O4S2 and molecular weight 318.99 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-amino-6-(trifluoromethyl)benzene-1,3-disulfonamide

Also Known As: 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide, 2,4-Disulfamyl-5-trifluoromethylaniline, 2pow, 2-amino-4-trifluoromethyl-1,5-benzendisulfonamide, Bendroflumethiazide EP Impurity A

CAS: 654-62-6
Molecular Formula C7H8F3N3O4S2
Molecular Weight 318.99 g/mol
LogP -0.2
Topological Polar Surface Area 163.0 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 10
Rotatable Bonds 2
Exact Mass 318.99084
Heavy Atoms 19
Complexity 533.0

Chemical Identifiers

CAS Number 654-62-6
SMILES C1=C(C(=CC(=C1N)S(=O)(=O)N)S(=O)(=O)N)C(F)(F)F
InChIKey KRVABEGPNKGLOT-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (12 patents) Organometallic Reagents (2 patents) Peptides & Amino Acids (2 patents) Pharmaceutical Intermediates (7 patents)

Product Overview

4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide (CAS 654-62-6), with molecular formula C7H8F3N3O4S2 and molecular weight 318.99 g/mol. IUPAC: 4-amino-6-(trifluoromethyl)benzene-1,3-disulfonamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide

XLogP
-0.2
TPSA (Topological Polar Surface Area)
163.0
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
10
Rotatable Bonds
2
Heavy Atoms
19
Complexity
533.0
Exact Mass
318.99084
Monoisotopic Mass
318.99084
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide

The XLogP value of -0.2 indicates that 4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 163.0 Ų indicates high polarity, suggesting 4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide has 3 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide?

The CAS number of 4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide is 654-62-6.

What is the molecular formula of 4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide?

The molecular formula of 4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide is C7H8F3N3O4S2.

What is the molecular weight of 4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide?

The molecular weight of 4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide is 318.99 g/mol.

Where can I buy 4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide?

You can request a quote for 4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide?

Yes, KEHONG BIO provides custom synthesis services for 4-Amino-6-(trifluoromethyl)-1,3-benzenedisulfonamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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