Phenylalanyl-prolyl-arginine-chloromethyl ketone
TL;DR: Phenylalanyl-prolyl-arginine-chloromethyl ketone (CAS 65149-23-7) is a chemical compound with molecular formula C21H31ClN6O3 and molecular weight 450.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-N-[(2S)-1-[[(3S)-1-chloro-6-(diaminomethylideneamino)-2-oxohexan-3-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide
Also Known As: Fprmecl, Phe-pro-arg-CK, FPRCK, Phe-pro-arg-CH2-Cl, PPACK
| Molecular Formula | C21H31ClN6O3 |
|---|---|
| Molecular Weight | 450.21 g/mol |
| LogP | -0.5 |
| Topological Polar Surface Area | 152.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 12 |
| Exact Mass | 450.21463 |
| Heavy Atoms | 31 |
| Complexity | 635.0 |
Chemical Identifiers
| CAS Number | 65149-23-7 |
|---|---|
| SMILES | C1C[C@H](NC1)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CCCN=C(N)N)C(=O)CCl |
| InChIKey | HCCRRLVJBLDSLL-ULQDDVLXSA-N |
Product Overview
Phenylalanyl-prolyl-arginine-chloromethyl ketone (CAS 65149-23-7), with molecular formula C21H31ClN6O3 and molecular weight 450.21 g/mol. IUPAC: (2S)-N-[(2S)-1-[[(3S)-1-chloro-6-(diaminomethylideneamino)-2-oxohexan-3-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide.
Chemical Property Profile of Phenylalanyl-prolyl-arginine-chloromethyl ketone
Property Insights of Phenylalanyl-prolyl-arginine-chloromethyl ketone
The XLogP value of -0.5 indicates that Phenylalanyl-prolyl-arginine-chloromethyl ketone is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 152.0 Ų indicates high polarity, suggesting Phenylalanyl-prolyl-arginine-chloromethyl ketone may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Phenylalanyl-prolyl-arginine-chloromethyl ketone has 5 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Phenylalanyl-prolyl-arginine-chloromethyl ketone?
The CAS number of Phenylalanyl-prolyl-arginine-chloromethyl ketone is 65149-23-7.
What is the molecular formula of Phenylalanyl-prolyl-arginine-chloromethyl ketone?
The molecular formula of Phenylalanyl-prolyl-arginine-chloromethyl ketone is C21H31ClN6O3.
What is the molecular weight of Phenylalanyl-prolyl-arginine-chloromethyl ketone?
The molecular weight of Phenylalanyl-prolyl-arginine-chloromethyl ketone is 450.21 g/mol.
Where can I buy Phenylalanyl-prolyl-arginine-chloromethyl ketone?
You can request a quote for Phenylalanyl-prolyl-arginine-chloromethyl ketone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Phenylalanyl-prolyl-arginine-chloromethyl ketone?
Yes, KEHONG BIO provides custom synthesis services for Phenylalanyl-prolyl-arginine-chloromethyl ketone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.