![2-{4-[4-(Trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-ol structure](/static/products/6510/651004-99-8.webp)
2-{4-[4-(Trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-ol
TL;DR: 2-{4-[4-(Trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-ol (CAS 651004-99-8) is a chemical compound with molecular formula C11H15F3N4O and molecular weight 276.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[4-[4-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]ethanol
Also Known As: Maybridge1_000493, 2-{4-[4-(trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-ol, 2-(4-(4-(Trifluoromethyl)pyrimidin-2-yl)piperazin-1-yl)ethanol, 2-[4-[4-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]ethanol, 2-{4-[4-(TRIFLUOROMETHYL)PYRIMIDIN-2-YL]PIPERAZIN-1-YL}ETHANOL
| Molecular Formula | C11H15F3N4O |
|---|---|
| Molecular Weight | 276.12 g/mol |
| LogP | 0.6097 |
| Topological Polar Surface Area | 52.49 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 276.11978 |
| Heavy Atoms | 19 |
| Complexity | 418.64648 |
Chemical Identifiers
| CAS Number | 651004-99-8 |
|---|---|
| SMILES | C1CN(CCN1CCO)C2=NC=CC(=N2)C(F)(F)F |
Product Overview
2-{4-[4-(Trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-ol (CAS 651004-99-8), with molecular formula C11H15F3N4O and molecular weight 276.12 g/mol. IUPAC: 2-[4-[4-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]ethanol.
Chemical Property Profile of 2-{4-[4-(Trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-ol
Property Insights of 2-{4-[4-(Trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-ol
The XLogP value of 0.6097 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-{4-[4-(Trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-ol. With a topological polar surface area (TPSA) of 52.49 Ų, 2-{4-[4-(Trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-ol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-{4-[4-(Trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-ol has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-{4-[4-(Trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-ol?
The CAS number of 2-{4-[4-(Trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-ol is 651004-99-8.
What is the molecular formula of 2-{4-[4-(Trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-ol?
The molecular formula of 2-{4-[4-(Trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-ol is C11H15F3N4O.
What is the molecular weight of 2-{4-[4-(Trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-ol?
The molecular weight of 2-{4-[4-(Trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-ol is 276.12 g/mol.
Where can I buy 2-{4-[4-(Trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-ol?
You can request a quote for 2-{4-[4-(Trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-{4-[4-(Trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-ol?
Yes, KEHONG BIO provides custom synthesis services for 2-{4-[4-(Trifluoromethyl)pyrimidin-2-yl]piperazino}ethan-1-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.