3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine
TL;DR: 3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine (CAS 64911-18-8) is a chemical compound with molecular formula C21H40N2O5Si2 and molecular weight 456.25 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[4-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]oxolan-2-yl]pyrimidine-2,4-dione
Also Known As: 3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine, 3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine, 1-[4-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]oxolan-2-yl]pyrimidine-2,4-dione
| Molecular Formula | C21H40N2O5Si2 |
|---|---|
| Molecular Weight | 456.25 g/mol |
| LogP | 4.2363 |
| Topological Polar Surface Area | 77.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 8 |
| Exact Mass | 456.2476 |
| Heavy Atoms | 30 |
| Complexity | 694.0 |
Chemical Identifiers
| CAS Number | 64911-18-8 |
|---|---|
| SMILES | CC(C)(C)[Si](C)(C)OCC1C(CC(O1)N2C=CC(=O)NC2=O)O[Si](C)(C)C(C)(C)C |
| InChIKey | DKEAALKCPSPQCU-UHFFFAOYSA-N |
Product Overview
3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine (CAS 64911-18-8), with molecular formula C21H40N2O5Si2 and molecular weight 456.25 g/mol. IUPAC: 1-[4-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]oxolan-2-yl]pyrimidine-2,4-dione.
Chemical Property Profile of 3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine
Property Insights of 3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine
The XLogP value of 4.2363 indicates that 3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 77.1 Ų falls within the moderate polarity range, balancing permeability and solubility for 3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine. Following Lipinski's Rule of Five, 3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine?
The CAS number of 3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine is 64911-18-8.
What is the molecular formula of 3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine?
The molecular formula of 3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine is C21H40N2O5Si2.
What is the molecular weight of 3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine?
The molecular weight of 3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine is 456.25 g/mol.
Where can I buy 3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine?
You can request a quote for 3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine?
Yes, KEHONG BIO provides custom synthesis services for 3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.