3-(glutathion-S-yl)acetaminophen structure

3-(glutathion-S-yl)acetaminophen

TL;DR: 3-(glutathion-S-yl)acetaminophen (CAS 64889-81-2) is a chemical compound with molecular formula C18H24N4O8S and molecular weight 456.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-5-[[(2R)-3-(5-acetamido-2-hydroxyphenyl)sulfanyl-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-2-amino-5-oxopentanoic acid

Also Known As: AA-Glutathion, AA-Gsh, Acetaminophen glutathion, 3-Gsh-acetaminophen, 3-(Glutathion-S-yl)acetaminophen

CAS: 64889-81-2
Molecular Formula C18H24N4O8S
Molecular Weight 456.13 g/mol
LogP -3.8
Topological Polar Surface Area 233.0 Ų
Hydrogen Bond Donors 7
Hydrogen Bond Acceptors 10
Rotatable Bonds 12
Exact Mass 456.13147
Heavy Atoms 31
Complexity 677.0

Chemical Identifiers

CAS Number 64889-81-2
SMILES CC(=O)NC1=CC(=C(C=C1)O)SC[C@@H](C(=O)NCC(=O)O)NC(=O)CC[C@@H](C(=O)O)N
InChIKey VFNAXGMNFCUWCI-RYUDHWBXSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Organic Building Blocks (4 patents) Pharmaceutical Intermediates (3 patents)

Product Overview

3-(glutathion-S-yl)acetaminophen (CAS 64889-81-2), with molecular formula C18H24N4O8S and molecular weight 456.13 g/mol. IUPAC: (2S)-5-[[(2R)-3-(5-acetamido-2-hydroxyphenyl)sulfanyl-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-2-amino-5-oxopentanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 3-(glutathion-S-yl)acetaminophen

XLogP
-3.8
TPSA (Topological Polar Surface Area)
233.0
Hydrogen Bond Donors
7
Hydrogen Bond Acceptors
10
Rotatable Bonds
12
Heavy Atoms
31
Complexity
677.0
Exact Mass
456.13147
Monoisotopic Mass
456.13147
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 3-(glutathion-S-yl)acetaminophen

The XLogP value of -3.8 indicates that 3-(glutathion-S-yl)acetaminophen is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 233.0 Ų indicates high polarity, suggesting 3-(glutathion-S-yl)acetaminophen may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 3-(glutathion-S-yl)acetaminophen has 7 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 3-(glutathion-S-yl)acetaminophen?

The CAS number of 3-(glutathion-S-yl)acetaminophen is 64889-81-2.

What is the molecular formula of 3-(glutathion-S-yl)acetaminophen?

The molecular formula of 3-(glutathion-S-yl)acetaminophen is C18H24N4O8S.

What is the molecular weight of 3-(glutathion-S-yl)acetaminophen?

The molecular weight of 3-(glutathion-S-yl)acetaminophen is 456.13 g/mol.

Where can I buy 3-(glutathion-S-yl)acetaminophen?

You can request a quote for 3-(glutathion-S-yl)acetaminophen directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 3-(glutathion-S-yl)acetaminophen?

Yes, KEHONG BIO provides custom synthesis services for 3-(glutathion-S-yl)acetaminophen and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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