![4-[5-(4-fluorophenyl)pyridin-3-yl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine structure](/static/products/6483/6483-66-5.webp)
4-[5-(4-fluorophenyl)pyridin-3-yl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine
TL;DR: 4-[5-(4-fluorophenyl)pyridin-3-yl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine (CAS 6483-66-5) is a chemical compound with molecular formula C25H23FN6 and molecular weight 426.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[5-(4-fluorophenyl)-3-pyridinyl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine
Also Known As: 4-[5-(4-fluorophenyl)pyridin-3-yl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine, 4-[5-(4-Fluorophenyl)pyridin-3-yl]-2-methyl-6-[4-(pyridin-2-yl)piperazin-1-yl]pyrimidine
| Molecular Formula | C25H23FN6 |
|---|---|
| Molecular Weight | 426.20 g/mol |
| LogP | 4.37472 |
| Topological Polar Surface Area | 58.04 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 426.1968 |
| Heavy Atoms | 32 |
| Complexity | 1204.7972 |
Chemical Identifiers
| CAS Number | 6483-66-5 |
|---|---|
| SMILES | CC1=NC(=CC(=N1)N2CCN(CC2)C3=CC=CC=N3)C4=CN=CC(=C4)C5=CC=C(C=C5)F |
Product Overview
4-[5-(4-fluorophenyl)pyridin-3-yl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine (CAS 6483-66-5), with molecular formula C25H23FN6 and molecular weight 426.20 g/mol. IUPAC: 4-[5-(4-fluorophenyl)-3-pyridinyl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine.
Chemical Property Profile of 4-[5-(4-fluorophenyl)pyridin-3-yl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine
Property Insights of 4-[5-(4-fluorophenyl)pyridin-3-yl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine
The XLogP value of 4.37472 indicates that 4-[5-(4-fluorophenyl)pyridin-3-yl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.04 Ų, 4-[5-(4-fluorophenyl)pyridin-3-yl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-[5-(4-fluorophenyl)pyridin-3-yl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-[5-(4-fluorophenyl)pyridin-3-yl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine?
The CAS number of 4-[5-(4-fluorophenyl)pyridin-3-yl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine is 6483-66-5.
What is the molecular formula of 4-[5-(4-fluorophenyl)pyridin-3-yl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine?
The molecular formula of 4-[5-(4-fluorophenyl)pyridin-3-yl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine is C25H23FN6.
What is the molecular weight of 4-[5-(4-fluorophenyl)pyridin-3-yl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine?
The molecular weight of 4-[5-(4-fluorophenyl)pyridin-3-yl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine is 426.20 g/mol.
Where can I buy 4-[5-(4-fluorophenyl)pyridin-3-yl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine?
You can request a quote for 4-[5-(4-fluorophenyl)pyridin-3-yl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-[5-(4-fluorophenyl)pyridin-3-yl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine?
Yes, KEHONG BIO provides custom synthesis services for 4-[5-(4-fluorophenyl)pyridin-3-yl]-2-methyl-6-(4-pyridin-2-ylpiperazin-1-yl)pyrimidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.