2(1H)-Quinazolinone, 6-((difluoromethyl)thio)-4-phenyl-
TL;DR: 2(1H)-Quinazolinone, 6-((difluoromethyl)thio)-4-phenyl- (CAS 64820-49-1) is a chemical compound with molecular formula C15H10F2N2OS and molecular weight 304.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-(difluoromethylsulfanyl)-4-phenyl-1H-quinazolin-2-one
Also Known As: 2(1H)-Quinazolinone, 6-((difluoromethyl)thio)-4-phenyl-, 6-[(difluoromethyl)thio]-4-phenyl-2(1H)-quinazolinone, 5-25-02-00215 (Beilstein Handbook Reference), 6-((Difluoromethyl)thio)-4-phenyl-2(1H)-quinazolinone, 6-difluoromethylthio-4-phenylquinazolin-2-one
| Molecular Formula | C15H10F2N2OS |
|---|---|
| Molecular Weight | 304.05 g/mol |
| LogP | 3.5 |
| Topological Polar Surface Area | 66.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 304.0482 |
| Heavy Atoms | 21 |
| Complexity | 424.0 |
| Solubility | 1.4 [ug/mL] (The mean of the results at pH 7.4) |
Chemical Identifiers
| CAS Number | 64820-49-1 |
|---|---|
| SMILES | C1=CC=C(C=C1)C2=NC(=O)NC3=C2C=C(C=C3)SC(F)F |
| InChIKey | OJZOQFOCMUIHOG-UHFFFAOYSA-N |
Product Overview
2(1H)-Quinazolinone, 6-((difluoromethyl)thio)-4-phenyl- (CAS 64820-49-1), with molecular formula C15H10F2N2OS and molecular weight 304.05 g/mol. IUPAC: 6-(difluoromethylsulfanyl)-4-phenyl-1H-quinazolin-2-one.
Chemical Property Profile of 2(1H)-Quinazolinone, 6-((difluoromethyl)thio)-4-phenyl-
Property Insights of 2(1H)-Quinazolinone, 6-((difluoromethyl)thio)-4-phenyl-
The XLogP value of 3.5 indicates that 2(1H)-Quinazolinone, 6-((difluoromethyl)thio)-4-phenyl- is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.8 Ų falls within the moderate polarity range, balancing permeability and solubility for 2(1H)-Quinazolinone, 6-((difluoromethyl)thio)-4-phenyl-. Following Lipinski's Rule of Five, 2(1H)-Quinazolinone, 6-((difluoromethyl)thio)-4-phenyl- has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2(1H)-Quinazolinone, 6-((difluoromethyl)thio)-4-phenyl-?
The CAS number of 2(1H)-Quinazolinone, 6-((difluoromethyl)thio)-4-phenyl- is 64820-49-1.
What is the molecular formula of 2(1H)-Quinazolinone, 6-((difluoromethyl)thio)-4-phenyl-?
The molecular formula of 2(1H)-Quinazolinone, 6-((difluoromethyl)thio)-4-phenyl- is C15H10F2N2OS.
What is the molecular weight of 2(1H)-Quinazolinone, 6-((difluoromethyl)thio)-4-phenyl-?
The molecular weight of 2(1H)-Quinazolinone, 6-((difluoromethyl)thio)-4-phenyl- is 304.05 g/mol.
Where can I buy 2(1H)-Quinazolinone, 6-((difluoromethyl)thio)-4-phenyl-?
You can request a quote for 2(1H)-Quinazolinone, 6-((difluoromethyl)thio)-4-phenyl- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2(1H)-Quinazolinone, 6-((difluoromethyl)thio)-4-phenyl-?
Yes, KEHONG BIO provides custom synthesis services for 2(1H)-Quinazolinone, 6-((difluoromethyl)thio)-4-phenyl- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.