pyroglutamyl-L-histidyl-L-pipecolic acid amide
TL;DR: pyroglutamyl-L-histidyl-L-pipecolic acid amide (CAS 64783-96-6) is a chemical compound with molecular formula C17H24N6O4 and molecular weight 376.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]piperidine-2-carboxamide
Also Known As: Pglu-his-pipecolic acid amide, Pyroglutamyl-L-histidyl-L-pipecolic acid amide, 2-Piperidinecarboxamide, 1-(N-(5-oxo-L-prolyl)-L-histidyl)-, 1-(N-{Hydroxy[(2S)-5-hydroxy-3,4-dihydro-2H-pyrrol-2-yl]methylidene}-L-histidyl)piperidine-2-carboximidic acid, 1-[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]piperidine-2-carboxamide
| Molecular Formula | C17H24N6O4 |
|---|---|
| Molecular Weight | 376.19 g/mol |
| LogP | -1.418 |
| Topological Polar Surface Area | 150.28 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 376.1859 |
| Heavy Atoms | 27 |
| Complexity | 719.0156 |
Chemical Identifiers
| CAS Number | 64783-96-6 |
|---|---|
| SMILES | C1CCN(C(C1)C(=O)N)C(=O)[C@H](CC2=CN=CN2)NC(=O)[C@@H]3CCC(=O)N3 |
Product Overview
pyroglutamyl-L-histidyl-L-pipecolic acid amide (CAS 64783-96-6), with molecular formula C17H24N6O4 and molecular weight 376.19 g/mol. IUPAC: 1-[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]piperidine-2-carboxamide.
Chemical Property Profile of pyroglutamyl-L-histidyl-L-pipecolic acid amide
Property Insights of pyroglutamyl-L-histidyl-L-pipecolic acid amide
The XLogP value of -1.418 indicates that pyroglutamyl-L-histidyl-L-pipecolic acid amide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 150.28 Ų indicates high polarity, suggesting pyroglutamyl-L-histidyl-L-pipecolic acid amide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, pyroglutamyl-L-histidyl-L-pipecolic acid amide has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of pyroglutamyl-L-histidyl-L-pipecolic acid amide?
The CAS number of pyroglutamyl-L-histidyl-L-pipecolic acid amide is 64783-96-6.
What is the molecular formula of pyroglutamyl-L-histidyl-L-pipecolic acid amide?
The molecular formula of pyroglutamyl-L-histidyl-L-pipecolic acid amide is C17H24N6O4.
What is the molecular weight of pyroglutamyl-L-histidyl-L-pipecolic acid amide?
The molecular weight of pyroglutamyl-L-histidyl-L-pipecolic acid amide is 376.19 g/mol.
Where can I buy pyroglutamyl-L-histidyl-L-pipecolic acid amide?
You can request a quote for pyroglutamyl-L-histidyl-L-pipecolic acid amide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for pyroglutamyl-L-histidyl-L-pipecolic acid amide?
Yes, KEHONG BIO provides custom synthesis services for pyroglutamyl-L-histidyl-L-pipecolic acid amide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.