Coleonol
TL;DR: Coleonol (CAS 64657-11-0) is a chemical compound with molecular formula C22H34O7 and molecular weight 410.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(3R,4aR,5R,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] acetate
Also Known As: Coleonol, forskolin, Colforsin, NCI60_003231, [(3R,4aR,5R,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] acetate
| Molecular Formula | C22H34O7 |
|---|---|
| Molecular Weight | 410.23 g/mol |
| LogP | 1.0 |
| Topological Polar Surface Area | 113.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 3 |
| Exact Mass | 410.23044 |
| Heavy Atoms | 29 |
| Complexity | 747.0 |
Chemical Identifiers
| CAS Number | 64657-11-0 |
|---|---|
| SMILES | CC(=O)O[C@@H]1[C@H]([C@@H]2[C@]([C@H](CCC2(C)C)O)([C@@]3([C@@]1(O[C@@](CC3=O)(C)C=C)C)O)C)O |
| InChIKey | OHCQJHSOBUTRHG-WWVGWVLGSA-N |
Product Overview
Coleonol (CAS 64657-11-0), with molecular formula C22H34O7 and molecular weight 410.23 g/mol. IUPAC: [(3R,4aR,5R,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] acetate.
Chemical Property Profile of Coleonol
Property Insights of Coleonol
The XLogP value of 1.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Coleonol. The TPSA of 113.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Coleonol. Following Lipinski's Rule of Five, Coleonol has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Coleonol?
The CAS number of Coleonol is 64657-11-0.
What is the molecular formula of Coleonol?
The molecular formula of Coleonol is C22H34O7.
What is the molecular weight of Coleonol?
The molecular weight of Coleonol is 410.23 g/mol.
Where can I buy Coleonol?
You can request a quote for Coleonol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Coleonol?
Yes, KEHONG BIO provides custom synthesis services for Coleonol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.